Abstract: |
The diagnosis of papillary thyroid microcarcinoma (PTMC) has increased over the last two decades due to over diagnosis. PTMC is defined as nodules <10 mm in size, categorizing the disease as a subclinical process. The traditional therapeutic option for this patient population was thyroidectomy until active surveillance became a viable alternative to surgical resection. Of the patients that are diagnosed, approximately 50% are unwilling to undergo surveillance and opt for surgical intervention. Thyroid surgery, either lobectomy or total thyroidectomy, does have risks associated with the procedure including recurrent laryngeal nerve injury, permanent hypothyroidism and paresthesia’s of the anterior neck. An alternative to surgical resection is needed for patients that are unwilling to undergo observation. Furthermore, there is a subset of patients with recurrent thyroid cancer or locoregional lymph node metastasis that are unable to undergo surgical reintervention due to patient preference or medical comorbidities. In this chapter we discuss the current evidence of several minimally invasive, non-surgical thermal treatment options, such as percutaneous laser ablation, radiofrequency ablation and microwave ablation in the management of primary and recurrent thyroid cancer as a substitute for surgery. We will also discuss the technical considerations, patient selection, potential complications and reported outcomes of thermal ablation. Additionally, we will mention future trends in thyroid cancer ablation in combination with immunotherapy. © Springer Nature Switzerland AG 2020. |