Update of radiofrequency ablation for treating benign and malignant thyroid nodules. The future is now Review


Authors: Tufano, R. P.; Pace-Asciak, P.; Russell, J. O.; Suárez, C.; Randolph, G. W.; López, F.; Shaha, A. R.; Mäkitie, A.; Rodrigo, J. P.; Kowalski, L. P.; Zafereo, M.; Angelos, P.; Ferlito, A.; for the International Head and Neck Scientific Group
Review Title: Update of radiofrequency ablation for treating benign and malignant thyroid nodules. The future is now
Abstract: Thermal and chemical ablation are minimally invasive procedures that avoid removal of the thyroid gland and target symptomatic nodules directly. Internationally, Radiofrequency ablation (RFA) is among one of the most widely used thermal ablative techniques, and is gaining traction in North America. Surgery remains the standard of care for most thyroid cancer, and in the right clinical setting, Active Surveillance (AS) can be a reasonable option for low risk disease. Minimally invasive techniques have emerged as an alternative option for patients deemed high risk for surgery, or for those patients who wish to receive a more active treatment approach compared to AS. Herein, we review the literature on the safety and efficacy of RFA for treating benign non-functioning thyroid nodules, autonomously functioning thyroid nodules, primary small low risk thyroid cancer (namely papillary thyroid cancer) as well as recurrent thyroid cancer. © Copyright © 2021 Tufano, Pace-Asciak, Russell, Suárez, Randolph, López, Shaha, Mäkitie, Rodrigo, Kowalski, Zafereo, Angelos and Ferlito.
Keywords: radiofrequency ablation; thermal ablation; recurrent thyroid cancer; autonomously functioning thyroid nodules; benign thyroid nodules; primary thyroid cancer
Journal Title: Frontiers in Endocrinology
Volume: 12
ISSN: 1664-2392
Publisher: Frontiers Media S.A.  
Date Published: 2021-06-24
Start Page: 698689
Language: English
DOI: 10.3389/fendo.2021.698689
PROVIDER: scopus
PMCID: PMC8264548
PUBMED: 34248853
DOI/URL:
Notes: Review -- Export Date: 2 August 2021 -- Source: Scopus
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  1. Ashok R Shaha
    697 Shaha