Minimum requirements to safely establish and sustain new hepatic arterial infusion pump programs: An international expert perspective Review


Authors: Merkow, R. P.; Cavnar, M. J.; Gleisner, A. L.; Mayo, S. C.; Gholami, S.; Karanicolas, P. J.; Koerkamp, B. G.; Homs, M. Y. V.; Connell, L. C.; Cercek, A.; Helft, P. R.; Polite, B. N.; Patel, R. A.; Uronis, H. E.; D’Angelica, M.; Lidsky, M. E.
Review Title: Minimum requirements to safely establish and sustain new hepatic arterial infusion pump programs: An international expert perspective
Abstract: Hepatic arterial infusion (HAI) pump chemotherapy is an effective therapy for colorectal liver metastases and intrahepatic cholangiocarcinoma. In the setting of recent reports suggesting favorable outcomes in these diseases with HAI, there has been a surge in interest in this treatment worldwide, prompting the opening of many new HAI programs. While significant technical expertise is required for pump implantation, this alone is insufficient to open a safe and sustainable HAI program, and numerous other factors must be considered prior to the first pump implantation. This expert perspective, established using an anonymous web-based survey of experienced multidisciplinary international HAI providers, details the minimum required personnel, expertise, training, and infrastructure to optimize success and sustainability of a safe and effective new HAI program. © Society of Surgical Oncology 2025.
Keywords: middle aged; review; liver neoplasms; pathology; colorectal neoplasms; colorectal tumor; liver tumor; intraarterial drug administration; infusions, intra-arterial; intrahepatic cholangiocarcinoma; bile duct carcinoma; bile duct neoplasms; cholangiocarcinoma; drug administration; drug therapy; therapy; hepatic artery; bile duct tumor; infusion pump; complication; devices; haip; colorectal liver metastasis; humans; human; hepatic artery infusion pump; adverse device effect; expert perspective; hai
Journal Title: Annals of Surgical Oncology
Volume: 32
Issue: 6
ISSN: 1068-9265
Publisher: Springer  
Date Published: 2025-06-01
Start Page: 4408
End Page: 4416
Language: English
DOI: 10.1245/s10434-025-17009-1
PUBMED: 39962001
PROVIDER: scopus
DOI/URL:
Notes: Review -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Louise Catherine Connell
    45 Connell