Synthesizing decomposed tumor images with a patient-specific conditional diffusion model to enhance tumor contrast for x-ray-guided radiotherapy Conference Paper


Authors: Peng, J.; Safari, M.; Qiu, R. L. J.; Roper, J.; Wang, T.; Yang, X.
Title: Synthesizing decomposed tumor images with a patient-specific conditional diffusion model to enhance tumor contrast for x-ray-guided radiotherapy
Conference Title: Medical Imaging 2025: Image-Guided Procedures, Robotic Interventions, and Modeling
Abstract: Real-time tumor tracking can monitor patient motion, verify tumor position, and guide the radiation beam to the tumor target in X-ray-guided radiation therapy. However, markerless kilovoltage (kV) X-ray image-based tumor tracking is a long-standing challenge in clinical practice due to its low tumor contrast and visibility. In this work, we aim to develop a patient-specific conditional diffusion model to generate the decomposed tumor image (DTI) for X-ray-guided tumor tracking in radiotherapy. The proposed method is evaluated using lung patients and can effectively improve the target contrast of lung tumors on the kV projection images. © 2025 SPIE
Journal Title Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume: 13408
Conference Dates: 2025 Feb 17-20
Conference Location: San Diego, CA
ISBN: 1605-7422
Publisher: SPIE  
Date Published: 2025-01-01
Start Page: 134082H
Language: English
DOI: 10.1117/12.3047403
PROVIDER: scopus
DOI/URL:
Notes: Conference paper (ISBN: 9781510685949) -- Source: Scopus
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  1. Tonghe Wang
    55 Wang