A hybrid method for reliable registration of digitally reconstructed radiographs and kV X-ray images for image-guided radiation therapy for prostate cancer Conference Paper
| Authors: | Song, Y.; Mueller, B.; Chan, M. F.; Sim, S. E.; Mychalczak, B.; Huang, X. |
| Title: | A hybrid method for reliable registration of digitally reconstructed radiographs and kV X-ray images for image-guided radiation therapy for prostate cancer |
| Conference Title: | Medical Imaging 2008: Visualization, Image-Guided Procedures, and Modeling |
| Abstract: | Prostate cancer is the most common tumor site treated with intensity modulated radiation therapy (IMRT). However, due to patient and organ motions, treatment-induced physiological changes, and different daily filling in the bladder and rectum, the position of the prostate in relation to the fixed pelvic bone can change significantly. Without a reliable guiding technique, this could result in underdosing the target and overdosing the critical organs. Therefore, image-guided localization of the prostate must be performed prior to each treatment, which led to the development of a new radiation treatment modality, the image-guided radiation therapy (1GRT). One form of IGRT is to implant three gold seed markers into the prostate gland to serve as a fixed reference system. Daily patient setup verification is performed by using the gold seed markers-based image registration rather than the commonly used bony landmarks-based approach. In this paper, we present an efficient and automated method for registering digitally reconstructed radiographs (DRR) and kV X-ray images of the prostate with high accuracy using a hybrid method. Our technique relies on both internal fiducial markers (i.e. gold seed markers) implanted into the prostate and a robust, hybrid 2D registration method using a salient-region based image registration technique. The registration procedure consists of several novel steps. Validation experiments were performed to register DRR and kV X-ray images in anterior-posterior (AP) or lateral views and the results were reviewed by experienced radiation oncology physicists. |
| Keywords: | radiation; radiotherapy; prostate cancer; image enhancement; imrt; medical imaging; tumors; radiation oncology; microfluidics; radiography; patient treatment; visualization; igrt; tissue; image registration; radiation treatments; x ray analysis; image-guided; seed; gold; imaging techniques; fiducial markers; x rays; image guided radiation therapy; patient setup; real time systems; computer networks; image-guided procedures; drr; gold seed marker; implanted fiducial marker; kv x-ray image; obi; rigid-body image registration; agricultural products; hybrid sensors; x ray apparatus; anterior-posterior (ap); critical organs; digitally reconstructed radiograph (drr); digitally reconstructed radiographs (drrs); filling in; high accuracy; hybrid methods; intensity modulated radiation therapy (imrp); one form; pelvic bone; prostate cancer (cap); prostate glands; reference systems; region based; registration methods; tumor site; x ray images |
| Journal Title | Proceedings of SPIE |
| Volume: | 6918 |
| Conference Dates: | 2008 Feb 17 |
| Conference Location: | San Diego, CA |
| ISBN: | 0277-786X |
| Publisher: | SPIE |
| Date Published: | 2008-01-01 |
| Start Page: | 69182W |
| Language: | English |
| DOI: | 10.1117/12.771315 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - Progress in Biomedical Optics and Imaging - Proceedings of SPIE - Progr. Biomed. Opt. Imaging Proc. SPIE - "Conference code: 72207" - "Export Date: 17 November 2011" - "Sponsors: The International Society for Optical Engineering (SPIE)" - 17 February 2008 through 19 February 2008 - "Source: Scopus" |
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190Chan -
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116Song
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