Leveraging real-world data to advance biomarker discovery and precision oncology Editorial
| Authors: | Luo, J.; Solit, D. B. |
| Title: | Leveraging real-world data to advance biomarker discovery and precision oncology |
| Abstract: | Precision oncology is predicated on the availability of robust biomarkers deployed at scale at the point of care. Although simple in conception, precision oncology often fails in practice because of the limitations of current diagnostic platforms, the emergence of drug resistance, and an incomplete understanding of cancer pathogenesis and the host immune response. Here, we discuss using real-world data, including exceptional responder analyses, to identify biomarkers of therapy response and strategies for overcoming barriers to the broader adoption of precision oncology paradigms. © 2025 Elsevier Inc. |
| Keywords: | treatment response; note; tumor marker; oncogene; data analysis; point of care testing; dna sequencing; human; personalized cancer therapy; molecular fingerprinting |
| Journal Title: | Cancer Cell |
| Volume: | 43 |
| Issue: | 4 |
| ISSN: | 1535-6108 |
| Publisher: | Cell Press |
| Date Published: | 2025-04-14 |
| Start Page: | 606 |
| End Page: | 610 |
| Language: | English |
| DOI: | 10.1016/j.ccell.2025.03.012 |
| PUBMED: | 40154486 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Note -- Source: Scopus |
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