The ugly: Metastatic colon cancer-surgical options Journal Article


Authors: Dossa, F.; Weiser, M. R.
Article Title: The ugly: Metastatic colon cancer-surgical options
Abstract: Over 50% of patients with colorectal cancer develop metastatic disease. Although systemic therapy remains the backbone of palliative treatment, select patients may be candidates for surgical resection with curative intent. Given increasing evidence of the association between metastasectomy and prolonged survival, surgery has acquired an increasingly central role in the management of liver, lung, and peritoneal metastases. This is compounded by accumulating advances in local and systemic treatments that have allowed for expansion of the resectability pool, bringing the potential for curative surgical treatment to increasing numbers of patients with stage IV disease. However, as the boundaries of resectability are pushed, patient selection and consideration of tumor-related and technical factors are imperative to the identification of patients for whom surgery would be of the greatest benefit. © 2024 Thieme All rights reserved.
Keywords: survival; colorectal cancer; metastasis; resection
Journal Title: Clinics in Colon and Rectal Surgery
Volume: 38
Issue: 3
ISSN: 1531-0043
Publisher: Thieme Publishing  
Date Published: 2024-05-01
Start Page: 219
End Page: 228
Language: English
DOI: 10.1055/s-0044-1787825
PROVIDER: scopus
PMCID: PMC12020648
PUBMED: 40291995
DOI/URL:
Notes: -- Source: Scopus
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  1. Martin R Weiser
    538 Weiser
  2. Fahima Dossa
    7 Dossa