Whole-breast radiotherapy after breast-conserving surgery Book Section
| Author: | Braunstein, L. Z. |
| Editors: | Urban, C.; Rietjens, M.; El-Tamer, M.; Sacchini, V. S. |
| Article/Chapter Title: | Whole-breast radiotherapy after breast-conserving surgery |
| Abstract: | Oncologic advances and the emergence of precision medicine have made organ preservation increasingly achievable in the definitive management of various cancers. Breast-conserving therapy (BCT) is one such paradigm that has emerged from sequential efforts in the basic, clinical, and translational domains. Since the Halstedian era of increasingly aggressive surgical resection, investigators have sought to employ wide-ranging innovations to improve outcomes while simultaneously mitigating the toxicities of curative treatment. Enhanced radiographic techniques, meticulous attention to surgical margins, improvements in systemic therapy, and revolutionary radiation approaches have all converged to supplant the necessity of mastectomy in many cases of early, localized breast cancer. Indeed, while breast-conserving surgery followed by adjuvant whole-breast radiation now portends outcomes similar to mastectomy in most cases, emerging populations may safely omit adjuvant therapy entirely. Thus, whereas breast cancer was historically managed with the radical mastectomy, limited surgical resection and well-tolerated adjuvant treatments now portend among the best outcomes of any disease in the sphere of oncology. Here, we discuss appropriate selection of patients for BCT and elaborate on the necessary considerations for success of this treatment approach. © Springer International Publishing AG, part of Springer Nature 2013, 2019 |
| Book Title: | Oncoplastic and Reconstructive Breast Surgery. 2nd ed |
| ISBN: | 978-3-319-62925-4 |
| Publisher: | Springer |
| Publication Place: | Cham, Switzerland |
| Date Published: | 2019-01-01 |
| Start Page: | 195 |
| End Page: | 203 |
| Language: | English |
| DOI: | 10.1007/978-3-319-62927-8_14 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Book chapter: 14 -- This chapter can be found under "Part I Basic Principles for Oncoplastic and Reconstructive Breast Surgery" -- Source: Scopus |
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
-
146Sacchini -
105El-Tamer -
169Braunstein
Related MSK Work