Controlled quantum well formation on DNA-wrapped carbon nanotubes via peroxide-mediated aryl diazonium reduction Journal Article

  


Authors: Piletsky, S. S.; Keblish, E. E.; Heller, D. A.
Article Title: Controlled quantum well formation on DNA-wrapped carbon nanotubes via peroxide-mediated aryl diazonium reduction
Abstract: Quantum well defect-modified single-walled carbon nanotubes are nanomaterials with wide-ranging applications in biosensing, imaging, quantum computing, and catalysis. The most common method for covalent functionalization of nanotubes for biosensing applications involves reactions with aryl diazonium salts to generate sp3 aryl defect sites, commonly followed by wrapping with single-stranded DNA for aqueous dispersion. We describe herein a rapid aryl diazonium functionalization reaction directly compatible with DNA-wrapped nanotubes, mediated by hydrogen peroxide. The reaction uses mild aqueous conditions at physiological pH and can be easily monitored in real-time via fluorescence analysis to control the degree of functionalization. Overall, this reaction greatly simplifies the production of covalently functionalized DNA-wrapped carbon nanotubes, expanding their potential for industrial and biomedical applications. © 2025 American Chemical Society.
Keywords: fluorescence; hydrogen peroxide; functionalization; carbon nanotubes; single-walled carbon nanotubes (swcn); functionalizations; physiological models; biosensing; single-walled carbon; diazonium; quantum well defects; photodissociation; diazonia; diazonium reduction; dna-wrapped; quantum computing; quantum well defect; quantum-wells; wide-ranging applications
Journal Title: Nano Letters
Volume: 25
Issue: 6
ISSN: 1530-6984
Publisher: American Chemical Society  
Date Published: 2025-02-12
Start Page: 2480
End Page: 2485
Language: English
DOI: 10.1021/acs.nanolett.4c06061
PROVIDER: scopus
PUBMED: 39898587
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85216844027&doi=10.1021%2facs.nanolett.4c06061&partnerID=40&md5=e7ed99ed64d412b5cb21cace105b8d52
Notes: The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF. Corresponding MSK author is Daniel A. Heller -- Source: Scopus
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MSK Authors
  1. Daniel Alan Heller
    112 Heller
  2. Stanislav Piletsky
    2 Piletsky
  3. Erin Keblish
    2 Keblish
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