Kidney disease in systemic amyloidosis: A review of amyloid, amyloid serum a protein, leukocyte chemotactic factor 2, and transthyretin amyloid Review


Authors: Chowdhury, R.; Shah, S.; Latcha, S.; Lobato, L.
Review Title: Kidney disease in systemic amyloidosis: A review of amyloid, amyloid serum a protein, leukocyte chemotactic factor 2, and transthyretin amyloid
Abstract: Systemic amyloidoses are a group of disorders that can be hereditary or acquired and have various renal manifestations and outcomes. Light chain amyloid has been considered the most common renal amyloid and, thus, has been the focus of substantial research and therapeutic interest but with improvement in diagnostic techniques. However, there has been growing interest in rarer forms of renal amyloid, including amyloid serum A protein, leukocyte chemotactic factor 2 amyloid, and transthyretin amyloid. In this review, we provide an update on diagnostics, renal outcomes, and therapeutic landscape in these specific types of amyloid. Copyright © 2024 The Author(s).
Keywords: intercellular signaling peptides and proteins; metabolism; kidney disease; amyloidosis; blood; signal peptide; transthyretin; prealbumin; kidney diseases; serum amyloid a; serum amyloid a protein; humans; human; onconephrology; glomerular disease; lect2 protein, human
Journal Title: Kidney360
Volume: 5
Issue: 12
ISSN: 2641-7650
Publisher: Wolters Kluwer Health, Inc  
Date Published: 2024-12-01
Start Page: 1925
End Page: 1937
Language: English
DOI: 10.34067/kid.0000000600
PUBMED: 39356570
PROVIDER: scopus
PMCID: PMC11687988
DOI/URL:
Notes: Source: Scopus
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  1. Sheron Latcha
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