Tumors of the vulva and vagina Book Section
| Authors: | Broach, V.; Leitao, M. M. |
| Editors: | Raghavan, D.; Ahluwalia, M. S.; Blanke, C. D.; Brown, J. B.; Kim, E. S.; Reaman, G. H.; Sekeres, M. A. |
| Article/Chapter Title: | Tumors of the vulva and vagina |
| Abstract: | Vulvar and vaginal cancers are the least common gynecological malignancies and comprise a number of different histological subtypes including squamous cell carcinoma, melanoma, basal cell carcinoma, sarcoma, and others. Risk factors for these cancers are dependent on histological type and can include human papillomavirus exposure, lichen sclerosis, race, and age. Radical surgery has traditionally been the mainstay of therapy. However, more conservative surgical excision and limited lymph node sampling have become more widely accepted as they have been shown to have excellent oncological outcomes while sparing surgical morbidity. Similarly, advances in systemic therapy, specifically with respect to immunotherapy for vulvar melanoma, have changed the treatment paradigm for many of these cancers. Successful treatment of vulvar and vaginal cancers requires a patient centered, multidisciplinary approach. © 2017 John Wiley & Sons Ltd. |
| Keywords: | squamous cell carcinoma; sentinel lymph node; melanoma; immunotherapy; vulvar cancer; human papillomavirus; pelvic exenteration; paget's disease; vaginal cancer; bartholin's gland; lichen sclerosis |
| Book Title: | Textbook of Uncommon Cancer. 5th ed |
| ISBN: | 9781119196204 |
| Publisher: | Wiley Blackwell |
| Publication Place: | Hoboken, NJ |
| Date Published: | 2017-01-01 |
| Start Page: | 643 |
| End Page: | 652 |
| Language: | English |
| DOI: | 10.1002/9781119196235.ch44 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Book chapter: 44 -- Source: Scopus |
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