Vulvar cancer, version 3.2024, NCCN Clinical Practice Guidelines in Oncology Guidelines


Authors: Abu-Rustum, N. R.; Yashar, C. M.; Arend, R.; Barber, E.; Bradley, K.; Brooks, R.; Campos, S. M.; Chino, J.; Chon, H. S.; Crispens, M. A.; Damast, S.; Fisher, C. M.; Frederick, P.; Gaffney, D. K.; Gaillard, S.; Giuntoli, R. 2nd; Glaser, S.; Holmes, J.; Howitt, B. E.; Kendra, K.; Lea, J.; Lee, N.; Mantia-Smaldone, G.; Mariani, A.; Mutch, D.; Nagel, C.; Nekhlyudov, L.; Podoll, M.; Rodabaugh, K.; Salani, R.; Schorge, J.; Siedel, J.; Sisodia, R.; Soliman, P.; Ueda, S.; Urban, R.; Wethington, S. L.; Wyse, E.; Zanotti, K.; McMillian, N.; Espinosa, S.
Title: Vulvar cancer, version 3.2024, NCCN Clinical Practice Guidelines in Oncology
Abstract: Vulvar cancer is annually diagnosed in an estimated 6,470 individuals and the vast majority are histologically squamous cell carcinomas. Vulvar cancer accounts for 5% to 8% of gynecologic malignancies. Known risk factors for vulvar cancer include increasing age, infection with human papillomavirus, cigarette smoking, inflammatory conditions affecting the vulva, and immunodeficiency. Most vulvar neoplasias are diagnosed at early stages. Rarer histologies exist and include melanoma, extramammary Paget's disease, Bartholin gland adenocarcinoma, verrucous carcinoma, basal cell carcinoma, and sarcoma. This manuscript discusses recommendations outlined in the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for treatments, surveillance, systemic therapy options, and gynecologic survivorship.
Keywords: adenocarcinoma; skin neoplasms; pathology; genital neoplasms, female; skin tumor; female genital tract tumor; vulvar neoplasms; paget skin disease; vulva tumor; humans; human; female; paget disease, extramammary
Journal Title: Journal of the National Comprehensive Cancer Network
Volume: 22
Issue: 2
ISSN: 1540-1405
Publisher: Harborside Press  
Date Published: 2024-03-01
Start Page: 117
End Page: 135
Language: English
DOI: 10.6004/jnccn.2024.0013
PUBMED: 38503056
PROVIDER: scopus
DOI/URL:
Notes: Article -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
Related MSK Work