Fertility outcomes post immune checkpoint inhibitor exposure Research Letter
| Authors: | Harrold, E. C.; Ogle, M.; O'Brien, E.; Wilde, C.; Sinopoli, J.; Weiss, J.; Martino, L.; Casson, A.; Kang, H. J.; Postow, M.; Cercek, A. |
| Title: | Fertility outcomes post immune checkpoint inhibitor exposure |
| Abstract: | Harrold et al. evaluate the fertility impact of checkpoint inhibitor (ICB) exposure, demonstrating that unlike in utero exposure, post-exposure conception appears to result in uncomplicated pregnancies and healthy progeny. They demonstrate contemporaneous monitoring of temporal female hormonal fluctuations before, on, and post ICB exposure and prior to successful embryo implantation. © 2024 Elsevier Inc. |
| Keywords: | letter; neoplasm; neoplasms; drug effect; immunology; progeny; pregnancy; drug therapy; fertility; drug exposure; nidation; immune checkpoint inhibitor; humans; human; female; immune checkpoint inhibitors; prenatal exposure |
| Journal Title: | Cancer Cell |
| Volume: | 42 |
| Issue: | 11 |
| ISSN: | 1535-6108 |
| Publisher: | Cell Press |
| Date Published: | 2024-11-11 |
| Start Page: | 1808 |
| End Page: | 1810 |
| Language: | English |
| DOI: | 10.1016/j.ccell.2024.10.005 |
| PUBMED: | 39486412 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Letter -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PDF -- MSK corresponding author is Andrea Cercek -- Source: Scopus |
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