Authors: | Janjigian, Y. Y.; Wolchok, J. D.; Ariyan, C. E. |
Title: | Eradicating micrometastases with immune checkpoint blockade: Strike while the iron is hot |
Abstract: | Immune checkpoint blockade (ICB) is transforming treatment for many cancers. While ICB alone initially demonstrated efficacy in patients with metastatic melanoma, it has expanded to other types and to earlier-stage cancers. We describe ICB history, mechanisms underlying variation in response, and how ICB is being integrated into adjuvant and neoadjuvant treatment approaches. © 2021 |
Journal Title: | Cancer Cell |
Volume: | 39 |
Issue: | 6 |
ISSN: | 1535-6108 |
Publisher: | Cell Press |
Date Published: | 2021-06-14 |
Start Page: | 738 |
End Page: | 742 |
Language: | English |
DOI: | 10.1016/j.ccell.2021.05.013 |
PUBMED: | 34129818 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Article -- Export Date: 1 July 2021 -- Source: Scopus |