Parotidectomy for deep lobe pleomorphic adenomas is associated with higher rates of complications and recurrence Journal Article
| Authors: | Levyn, H.; Subramanian, T.; Eagan, A.; Katabi, N.; Goldberg, J.; Scholfield, D. W.; Caxeiro, G. L.; Wong, R. J.; Cohen, M. A.; Shah, J. P.; Patel, S. G.; Ganly, I. |
| Article Title: | Parotidectomy for deep lobe pleomorphic adenomas is associated with higher rates of complications and recurrence |
| Abstract: | Background: Pleomorphic adenoma (PA) is a common parotid tumor, yet due to the relative rarity of deep lobe PA (DLPA), there is a paucity of information about its clinical presentation and surgical outcomes. Methods: We reviewed the charts of patients with previously untreated parotid PA between the years 1990 and 2015. Clinical parameters and surgical outcomes were compared between superficial lobe PA (SLPA) and DLPA. Results: The cohort comprised 147 cases of DLPA and 222 cases of SLPA. DLPA were larger (median 2.6 cm vs. 2.0 cm, p < 0.001), more often discovered incidentally on imaging (33%, n = 48) and had unique presentations (pharyngeal mass, dysphagia, otalgia). Postsurgical complications were more frequently observed in DLPA (41% vs. 30% in SLPA, p = 0.025), mainly transient facial nerve weakness. DLPA also showed higher recurrence rates (n = 6, 4.1% vs. n = 1, 0.4%, p = 0.016). Conclusions: Parotidectomy for DLPA carries a higher risk of complications and recurrence compared to SLPA. © 2024 Wiley Periodicals LLC. |
| Keywords: | adolescent; adult; treatment outcome; aged; aged, 80 and over; middle aged; retrospective studies; young adult; major clinical study; recurrence risk; cohort studies; neoplasm recurrence, local; cohort analysis; pathology; retrospective study; postoperative complication; postoperative complications; dysphagia; tumor recurrence; surgery; epidemiology; parotid gland; facial nerve paralysis; parotid neoplasms; facial nerve; symptoms; pleomorphic adenoma; adenoma, pleomorphic; parotidectomy; parotid gland tumor; otalgia; parapharyngeal space; benign mixed tumor; very elderly; humans; human; male; female; article; major salivary glands |
| Journal Title: | Head & Neck |
| Volume: | 46 |
| Issue: | 11 |
| ISSN: | 1043-3074 |
| Publisher: | John Wiley & Sons, Inc. |
| Date Published: | 2024-11-01 |
| Start Page: | 2853 |
| End Page: | 2860 |
| Language: | English |
| DOI: | 10.1002/hed.27840 |
| PUBMED: | 38850073 |
| PROVIDER: | scopus |
| PMCID: | PMC11473235 |
| DOI/URL: | |
| Notes: | The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PubMed record and PDF. Corresponding MSK author is Ian Ganly -- Source: Scopus |
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