A biobehavioral perspective on caring for allogeneic hematopoietic stem cell transplant survivors with graft-versus-host disease Journal Article
| Authors: | Lahijani, S.; Rueda-Lara, M.; McAndrew, N.; Nelson, A. M.; Guo, M.; Knight, J. M.; Wiener, L.; Miran, D. M.; Gray, T. F.; Keane, E. P.; Yek, M. H.; Sannes, T. S.; Applebaum, A. J.; Fank, P.; Babu, P.; Pozo-Kaderman, C.; Amonoo, H. L. |
| Article Title: | A biobehavioral perspective on caring for allogeneic hematopoietic stem cell transplant survivors with graft-versus-host disease |
| Abstract: | Among the potential complications of allogeneic hematopoietic stem cell transplantation (HSCT), graft-versus-host disease (GVHD) is common and associated with significant physical and psychosocial symptom burden. Despite substantial advances in GVHD treatment, the global immune suppression that frequently accompanies GVHD treatment also contributes to high rates of physical and emotional suffering and mortality. The complex manifestations of GVHD and its treatment warrant a multidisciplinary team-based approach to managing patients' multi-organ system comorbidities. A biobehavioral framework can enhance our understanding of the complex association between medications, physical symptoms, and psychosocial distress in patients with GVHD. Hence, for this perspective, we highlight the importance of addressing both the physical and psychosocial needs experienced by patients with GVHD and provide guidance on how to approach and manage those symptoms and concerns as part of comprehensive cancer care. © 2024 The American Society for Transplantation and Cellular Therapy |
| Keywords: | adult; transplantation, homologous; fatigue; medical decision making; quality of life; pain; palliative therapy; psychology; hematopoietic stem cell transplantation; survivor; survivors; insomnia; patient care; depression; sexual dysfunction; graft versus host reaction; distress syndrome; posttraumatic stress disorder; allogeneic hematopoietic stem cell transplantation; cognitive defect; anxiety; age distribution; corticosteroid; graft vs host disease; geriatric patient; allotransplantation; pediatrics; psychosocial; adverse event; spiritual well-being; behavioral science; graft-versus-host disease; functioning; psychosocial intervention; demoralization; humans; human; article; well-being; psychological well-being; intersectoral collaboration; biobehavioral |
| Journal Title: | Transplantation and Cellular Therapy |
| Volume: | 30 |
| Issue: | 9 |
| ISSN: | 2666-6375 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2024-09-01 |
| Start Page: | S493 |
| End Page: | S512 |
| Language: | English |
| DOI: | 10.1016/j.jtct.2024.05.024 |
| PUBMED: | 39370233 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Source: Scopus |
