Five-year quality-of-life assessment by urinary diversion type after pelvic Exenterations Journal Article
| Authors: | Moufarrij, S.; Dagher, C.; Filippova, O. T.; Zhou, Q.; Iasonos, A.; Abu-Rustum, N. R.; Mueller, J. J.; Leitao, M. M.; Sandhu, J.; Bochner, B.; Carter, J.; Chi, D. S.; Sonoda, Y. |
| Article Title: | Five-year quality-of-life assessment by urinary diversion type after pelvic Exenterations |
| Abstract: | Objective: To determine whether urinary diversion procedures performed at time of pelvic exenteration affect quality of life in patients with recurrent gynecologic malignancies. Methods: We performed a retrospective secondary longitudinal analysis of quality of life according to type of urinary diversion patients received. Participants completed a series of validated questionnaires at various time points. We allocated patients based on urinary diversion type to either the continent group (CD; 29 [55 %]) or noncontinent group (NCD; 24 [45 %]). Results: We noted a significant improvement in global health scores from baseline over time (time p = 0.027). Physical functioning scores showed a statistically significant difference over time (at 24 months: NCD, −4.3 [95 % CI, −14.1 to 5.4]; CD, 0.4 [95 % CI, −7.1 to 7.9]. p < 0.001). Social functioning scores were persistently higher for the CD vs NCD group at all time points but did not differ significantly between the groups at baseline (p = 0.75) or over time within the same group (time p = 0.122). Body image scores significantly decreased (reduced burden) over time for both groups (p = 0.044) and were consistently higher in the NCD vs CD group. Conclusions: Patients experienced a return to their baseline quality of life within a year of surgery. Clinicians should prioritize and improve identifying and discussing postoperative challenges such as changes in physical and social functioning and body image. © 2024 |
| Keywords: | quality of life; urinary diversion; pelvic exenteration |
| Journal Title: | Gynecologic Oncology |
| Volume: | 191 |
| ISSN: | 0090-8258 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2024-12-01 |
| Start Page: | 212 |
| End Page: | 218 |
| Language: | English |
| DOI: | 10.1016/j.ygyno.2024.10.016 |
| PROVIDER: | scopus |
| PUBMED: | 39442374 |
| DOI/URL: | |
| Notes: | Article -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PDF -- MSK corresponding author is Yukio Sonoda -- Source: Scopus |
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