Quality of life outcomes after free fibula flap reconstruction of mandibular defects: A longitudinal examination Journal Article


Authors: Zhang, K. K.; Cohen, Z.; Cunningham, L.; Kim, M.; Monge, J.; Tecce, M.; Nelson, J. A.; Cracchiolo, J.; Matros, E.; Shahzad, F.; Allen, R. J. Jr
Article Title: Quality of life outcomes after free fibula flap reconstruction of mandibular defects: A longitudinal examination
Abstract: Background A comprehensive understanding of changes in health-related quality of life after head and neck cancer surgery is necessary for effective preoperative counseling. The goal of this study was to perform a longitudinal analysis of postoperative quality of life outcomes after fibula free flap (FFF) mandible reconstruction. Methods A retrospective review was performed for all patients who underwent oncologic mandible reconstruction with an FFF between 2000 and 2021. Completion of at least one postoperative FACE-Q questionnaire was necessary for inclusion. FACE-Q scores were divided into five time periods for analysis. Functional outcomes measured with speech language pathology (SLP) assessments and tracheostomy and gastrostomy tube status were analyzed at three time points. Results One hundred and nine patients were included. Of these, 68 patients also had at least one SLP assessment. All outcomes as measured by the various FACE-Q scales did not improve significantly from the immediate postoperative time point to the last evaluated time point (p > 0.05). SLP functional outcomes showed some deterioration over time, but these were not significant (p > 0.05). The percentage of patients who required a tracheostomy (18 to 2%, p 1⁄4 0.002) or gastrostomy tube (25 to 11%, p 1⁄4 0.035) decreased significantly from the immediate postoperative time point to the last evaluated time point. Conclusion Subjective quality of life outcomes do not change significantly with time after oncologic FFF mandible reconstruction. Reconstructive surgeons can use these results to help patients establish appropriate and achievable quality of life goals after surgery. Further studies are warranted to elucidate the impact of specific relevant clinical variables on postoperative quality of life. © 2024. Thieme. All rights reserved.
Keywords: adult; treatment outcome; aged; middle aged; patient satisfaction; functional assessment; retrospective studies; major clinical study; postoperative period; quality of life; cohort analysis; transplantation; retrospective study; questionnaire; longitudinal studies; surgery; free tissue graft; tracheostomy; longitudinal study; mandible; fibula; mandibular neoplasms; fibula graft; speech analysis; mandible reconstruction; mandible tumor; mandibular reconstruction; patient-reported outcome; free tissue flaps; procedures; fibula free flap; humans; human; male; female; article; jaw malformation; mandibulectomy; face q score
Journal Title: Journal of Reconstructive Microsurgery
Volume: 40
Issue: 8
ISSN: 0743-684X
Publisher: Thieme Medical Publishers, Inc.  
Date Published: 2024-10-01
Start Page: 578
End Page: 588
Language: English
DOI: 10.1055/a-2253-6208
PUBMED: 38267009
PROVIDER: scopus
DOI/URL:
Notes: Source: Scopus
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MSK Authors
  1. Evan Matros
    209 Matros
  2. Robert J Allen Jr
    102 Allen Jr
  3. Jonas Allan Nelson
    221 Nelson
  4. Farooq Shahzad
    39 Shahzad
  5. Zack Cohen
    7 Cohen
  6. Jasmine Monge
    7 Monge
  7. Kevin Kaiwen Zhang
    10 Zhang
  8. Minji Kim
    39 Kim
  9. Michael G Tecce
    1 Tecce