Clinical, functional, and patient-reported outcomes of radial forearm versus anterolateral thigh free tissue transfer for reconstruction of glossectomy defects Journal Article
| Authors: | Zhang, K. K.; Graziano, F. D.; Cohen, Z.; Cunningham, L.; Ali, B.; Coleman-Belin, J.; Kim, M.; Haglich, K.; Cracchiolo, J. R.; Matros, E.; Shahzad, F.; Nelson, J. A.; Allen, R. J. Jr |
| Article Title: | Clinical, functional, and patient-reported outcomes of radial forearm versus anterolateral thigh free tissue transfer for reconstruction of glossectomy defects |
| Abstract: | Background: There is a lack of literature of health-related quality of life endpoints for radial forearm (RF) versus anterolateral thigh (ALT) free flap reconstruction for glossectomy defects. Our goal was to perform a comprehensive evaluation of clinical, functional, and quality of life outcomes after glossectomy reconstruction using a RF or ALT flap. Methods: A retrospective review was performed on patients who underwent glossectomy and immediate reconstruction with RF or ALT flaps between 2016 and 2021. Outcomes of interest included readmission and reoperation rates, functional assessments, tracheostomy and gastrostomy tube status, and FACE-Q Head and Neck Cancer scores. Results: Seventy-eight patients consisting of 54 RF and 24 ALT free flaps were included. ALT patients had a larger median flap size (72 vs. 48 cm2, p = 0.021) and underwent mandibulotomy (50% vs. 7.4%, p < 0.0001) and base of tongue resection (58.3% vs. 24.1%, p = 0.005) at higher rates. No significant differences were found with respect to other outcomes. Conclusion: The RF and ALT flaps are suitable for glossectomy reconstruction, with minimal differences seen in postoperative outcomes. Our study suggests that ALT can be used in patients with base of tongue and larger defect sizes, while providing similar functional and clinical outcomes to RF reconstruction. © 2023 Wiley Periodicals LLC. |
| Keywords: | adolescent; adult; clinical article; controlled study; aged; middle aged; patient satisfaction; functional assessment; retrospective studies; anterolateral thigh flap; postoperative period; quality of life; retrospective study; questionnaire; thigh; head and neck cancer; reoperation; hospital readmission; patient reported outcome measures; free tissue graft; glossectomy; tongue tumor; tongue neoplasms; tracheostomy; functional status; mouth disease; forearm; clinical outcome; free flap; patient-reported outcome; free tissue flaps; procedures; facies; health-related quality of life (hrqol); humans; human; male; female; article; face-q; radial forearm flap; radial forearm; alt; mandibulectomy; face q questionnaire; glossectomy defect |
| Journal Title: | Journal of Surgical Oncology |
| Volume: | 129 |
| Issue: | 4 |
| ISSN: | 0022-4790 |
| Publisher: | Wiley Blackwell |
| Date Published: | 2024-03-15 |
| Start Page: | 681 |
| End Page: | 690 |
| Language: | English |
| DOI: | 10.1002/jso.27560 |
| PUBMED: | 38073188 |
| PROVIDER: | scopus |
| PMCID: | PMC11487476 |
| DOI/URL: | |
| Notes: | Article -- MSK corresponding author is Robert J. Allen Jr -- Source: Scopus |
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