How much time do focal treatments for retinoblastoma add to anesthetic exposure? Journal Article


Authors: Abramson, D. H.; Gaccione, J.; Bracken, C.; Liu, T.; Guarini, E.; Bobin, A.; Foerch, A.; Robbins, M. A.; Rojas, R. D.; Francis, J. H.
Article Title: How much time do focal treatments for retinoblastoma add to anesthetic exposure?
Abstract: Introduction: Children with retinoblastoma have anesthesia for exams and treatment, but there is little information about how long treatment interventions (laser, cryotherapy, and intravitreal injections) add to routine exams under anesthesia (EUA). This information would be useful for planning operating room schedules, staff schedules, family expectations, and billing. Methods: A retrospective, single-center, Institutional Review Board (IRB) approved review of anesthesia duration for retinoblastoma children undergoing EUA with laser, cryotherapy, or intravitreal injections performed at MSK between January 2019 and November 2023. Results: Three hundred eight patients had 2,399 EUAs. The average EUA lasted 24.3 min (range 7–77 min) when no interventions were done. Laser photocoagulation added an average of 18.9 min (range 19–77 min), cryotherapy 26.1 min (range 27–75 min), and intravitreal injection 23.5 min (range 10–71 min) to the basic EUA time. Bilateral laser treatments took 8 min longer than unilateral treatments. Conclusion: EUAs for children with retinoblastoma can be performed relatively quickly. Interventions such as laser, cryotherapy, or intravitreal injections roughly double the time under anesthesia but in some cases can take much longer (>1 h). © 2024 S. Karger AG, Basel.
Keywords: adult; controlled study; major clinical study; treatment duration; follow up; retinoblastoma; retrospective study; injection; quantitative analysis; laser coagulation; histogram; anesthesia; cryotherapy; laser therapy; laser; anesthetic agent; demographics; anesthesia induction; sevoflurane; human; male; female; article; fluorescence angiography; examination under anesthesia
Journal Title: Ocular Oncology and Pathology
Volume: 10
Issue: 3
ISSN: 2296-4681
Publisher: Karger  
Date Published: 2024-09-01
Start Page: 182
End Page: 188
Language: English
DOI: 10.1159/000539488
PROVIDER: scopus
PMCID: PMC11368391
PUBMED: 39224528
DOI/URL:
Notes: The MSK Cancer Center Support Grant (P30 CA008748) is acknowledge in the PDF -- Corresponding authors is MSK author: David H. Abramson -- Source: Scopus
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MSK Authors
  1. Jasmine Helen Francis
    261 Francis
  2. David H Abramson
    394 Abramson
  3. Todd Justin Liu
    5 Liu
  4. Andrea L Bobin
    2 Bobin
  5. Angela Marie Foerch
    2 Foerch