Dermatofibrosarcoma protuberans Book Section
| Authors: | Phillips, W.; Davis, M.; Nehal, K. S.; Connolly, K. |
| Editors: | McKay, C.; Nehal, K. S. |
| Article/Chapter Title: | Dermatofibrosarcoma protuberans |
| Abstract: | Dermatofibrosarcoma protuberans Dermatofibrosarcoma Protuberans (DFSP) is a slow growing rare soft tissue sarcoma with unpredictable subclinical extension. Although this malignant tumor is not specific to a specialized anatomic site, the processing of a DFSP specimen presents many challenges given large specimen size with extensive subcutaneous tissue. DFSPs account for an estimated 0.1% of all cancers with 42% of all cases occurring in 20-39 age range with a slightly higher incidence among women. DFSPs are most commonly located on the trunk and extremities and present as ill-defined large indurated plaques with minimal surface change. Histologically DFSP is a dermal proliferation of spindle cells with diffuse infiltration into the subcutis in a honeycomb pattern. Excising DFSP with Mohs surgery offers comprehensive margin control, and meticulous mapping of tumor margins is necessary to achieve high cure rates and tissue preservation. © The Author(s), Springer Nature Switzerland AG 2024. All rights reserved. |
| Keywords: | adipose tissue; dermatofibrosarcoma protuberans; specimen division; trimming; blocks and sectors; double-bladed scalpel; inking color scheme; large specimen processing |
| Book Title: | Laboratory manual for mohs micrographic surgery: Frozen tissue processing |
| ISBN: | 978-3-031-52433-2 |
| Publisher: | Springer |
| Publication Place: | Cham, Switzerland |
| Date Published: | 2024-01-01 |
| Start Page: | 149 |
| End Page: | 162 |
| Language: | English |
| DOI: | 10.1007/978-3-031-52434-9_13 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Source: Scopus |
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