Management of high-grade ovarian adenocarcinoma in an intraperitoneal pelvic renal transplant recipient Journal Article
| Authors: | Demirel, E.; Cohen, S.; Ennis, R. D.; Nezhat, F. R. |
| Article Title: | Management of high-grade ovarian adenocarcinoma in an intraperitoneal pelvic renal transplant recipient |
| Abstract: | Background: Number of organ transplant recipients continues to rise worldwide with increasing accessibility and growing advancements in transplant medicine. Transplant patients have at least a two-to-four fold higher risk of developing cancer compared to the general population. As the prevalence of transplant patients increases, a growing number of these patients are expected to present with concurrent conditions such as cancer, requiring more complex and interdisciplinary care. Case: A 44-year-old patient with an intraperitoneal pelvic renal transplant, found to have high-grade ovarian adenocarcinoma most likely arising from endometriosis, successfully underwent surgical staging, adjuvant chemotherapy, and subsequent pelvic radiation for recurrence. Her kidney function and graft viability were preserved throughout her treatment with careful monitoring. Conclusion: Management of reproductive tract cancers in kidney transplant recipients is complex. Current practices largely rely on evidence from observational studies and case reports for these cancers and more research is needed in this area. © 2024 The Authors |
| Keywords: | immunohistochemistry; adult; clinical article; human tissue; treatment response; unclassified drug; somatic mutation; drug tolerability; fatigue; histopathology; paresthesia; cancer recurrence; case report; cancer combination chemotherapy; multimodality cancer therapy; paclitaxel; cancer radiotherapy; cancer staging; nuclear magnetic resonance imaging; positron emission tomography; lymph node metastasis; paraaortic lymph node; pelvis lymph node; cytoreductive surgery; ovary adenocarcinoma; carboplatin; protein p16; multiple cycle treatment; thrombocytopenia; radiotherapy dosage; pelvis lymphadenectomy; peritoneal biopsy; peritoneum lavage; tumor differentiation; calcium; creatinine; creatinine blood level; patient monitoring; mutational analysis; brca2 protein; protein p53; tumor marker; wound healing; kidney function; adjuvant chemotherapy; echography; cancer size; hypermetabolism; reoperation; clinical decision making; cystoscopy; epithelial cell adhesion molecule; ca 125 antigen; wt1 protein; estrogen receptor; immunosuppressive treatment; tacrolimus; parathyroid hormone; surgical anatomy; uterus myoma; patient counseling; lymphadenopathy; graft recipient; cancer morphology; patient referral; hysteroscopy; dilatation and curettage; myomectomy; endometriosis; kidney graft rejection; kidney transplantation; ovary cyst; dermoid cyst; hepatocyte nuclear factor; obturator nerve; internal iliac artery; omentectomy; pelvis radiography; acetylcysteine; para-aortic lymphadenectomy; total laparoscopic hysterectomy; dysmenorrhea; human; female; article; pelvic pain; multidisciplinary team; robot assisted surgery; napsin; ovarian clear cell adenocarcinoma; patient under surveillance; bilateral salpingooophorectomy; adhesiolysis; bilateral nephrectomy; blood cyst; high grade ovarian adenocarcinoma; laparoscopic ovarian cystectomy; pelvic adhesion |
| Journal Title: | Gynecologic Oncology Reports |
| Volume: | 55 |
| ISSN: | 2352-5789 |
| Publisher: | Elsevier B.V. |
| Date Published: | 2024-09-30 |
| Start Page: | 101489 |
| Language: | English |
| DOI: | 10.1016/j.gore.2024.101489 |
| PROVIDER: | scopus |
| PMCID: | PMC11399701 |
| PUBMED: | 39281843 |
| DOI/URL: | |
| Notes: | Article -- Source: Scopus |
