Surgical radioguidance with beta-emitting radionuclides; Challenges and possibilities: A position paper by the EANM Review
| Authors: | Fragoso Costa, P.; Shi, K.; Holm, S.; Vidal-Sicart, S.; Kracmerova, T.; Tosi, G.; Grimm, J.; Visvikis, D.; Knapp, W. H.; Gnanasegaran, G.; van Leeuwen, F. W. B. |
| Review Title: | Surgical radioguidance with beta-emitting radionuclides; Challenges and possibilities: A position paper by the EANM |
| Abstract: | Radioguidance that makes use of β-emitting radionuclides is gaining in popularity and could have potential to strengthen the range of existing radioguidance techniques. While there is a strong tendency to develop new PET radiotracers, due to favorable imaging characteristics and the success of theranostics research, there are practical challenges that need to be overcome when considering use of β-emitters for surgical radioguidance. In this position paper, the EANM identifies the possibilities and challenges that relate to the successful implementation of β-emitters in surgical guidance, covering aspects related to instrumentation, radiation protection, and modes of implementation. © The Author(s) 2024. |
| Keywords: | unclassified drug; laparoscopic surgery; radiopharmaceuticals; radiation exposure; health care cost; chemistry; luminescence; radioactivity; fluorodeoxyglucose f 18; endoscopic surgery; radiopharmaceutical agent; nuclear medicine; radioactive tracers; tracer; radioisotope; drug therapy; radioisotopes; medical ethics; photon; electron; radiation protection; theranostics; surgery, computer-assisted; beta particles; image guided surgery; computer assisted surgery; procedures; radiotracer; open surgery; radiotracers; sodium iodide i 123; sodium iodide i 125; three-dimensional imaging; imaging characteristics; beta-emitting radionuclides; humans; human; article; destruction; surgical guidance; robot assisted surgery; edotreotide ga 68; dotanoc ga 68; gallium gozetotide ga 68; vipivotide tetraxetan lutetium lu 177; beta emitting radionuclides; radioguidance; edotreotide y 90; tilmanocept tc 99m; position papers; radiation mode |
| Journal Title: | European Journal of Nuclear Medicine and Molecular Imaging |
| Volume: | 51 |
| Issue: | 10 |
| ISSN: | 1619-7070 |
| Publisher: | Springer |
| Date Published: | 2024-08-01 |
| Start Page: | 2903 |
| End Page: | 2921 |
| Language: | English |
| DOI: | 10.1007/s00259-023-06560-2 |
| PUBMED: | 38189911 |
| PROVIDER: | scopus |
| PMCID: | PMC11300492 |
| DOI/URL: | |
| Notes: | Article -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PubMed and PDF -- Source: Scopus |
