Radiomics beyond the hype: A critical evaluation toward oncologic clinical use Review


Authors: Horvat, N.; Papanikolaou, N.; Koh, D. M.
Review Title: Radiomics beyond the hype: A critical evaluation toward oncologic clinical use
Abstract: Radiomics is a promising and fast-developing field within oncology that involves the mining of quantitative high-dimensional data from medical images. Radiomics has the potential to transform cancer management, whereby radiomics data can be used to aid early tumor characterization, prognosis, risk stratification, treatment planning, treatment response assessment, and surveillance. Nevertheless, certain challenges have delayed the clinical adoption and acceptability of radiomics in routine clinical practice. The objectives of this report are to (a) provide a perspective on the translational potential and potential impact of radiomics in oncology; (b) explore frequent challenges and mistakes in its derivation, encompassing study design, technical requirements, standardization, model reproducibility, transparency, data sharing, privacy concerns, quality control, as well as the complexity of multistep processes resulting in less radiologist-friendly interfaces; (c) discuss strategies to overcome these challenges and mistakes; and (d) propose measures to increase the clinical use and acceptability of radiomics, taking into account the different perspectives of patients, health care workers, and health care systems. © RSNA, 2024.
Keywords: treatment response; treatment planning; methodology; clinical practice; reproducibility; accuracy; quality control; gene expression; oncology; standardization; radiologist; algorithm; artificial intelligence; health care personnel; health care system; anxiety; knowledge; burnout; image segmentation; privacy; machine learning; learning algorithm; human; article; radiomics; cancer management
Journal Title: Radiology: Artificial Intelligence
Volume: 6
Issue: 4
ISSN: 2638-6100
Publisher: Radiological Society of North America, Inc.  
Date Published: 2024-07-01
Start Page: e230437
Language: English
DOI: 10.1148/ryai.230437
PROVIDER: scopus
PMCID: PMC11294952
PUBMED: 38717290
DOI/URL:
Notes: The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF -- Source: Scopus
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  1. Natally Horvat
    95 Horvat