The current (and possible future) role of opioid analgesia in lung cancer surgery Review
| Authors: | Pedoto, A.; Fischer, G. W.; Mincer, J. S. |
| Review Title: | The current (and possible future) role of opioid analgesia in lung cancer surgery |
| Abstract: | The objectives of this minireview are two-fold. The first is to discuss the evolution of opioid analgesia in perioperative medicine in the context of thoracic non-cardiac surgery. Current standard-of-care, aiming to optimize analgesia and limit undesirable side effects, is discussed in the context of multimodal analgesia, specifically enhanced recovery after thoracic surgery pathways. The second is to review a developing research program that may ultimately add another element to the personalization of analgesic plans for individual cancer patients based on optimizing oncological outcomes. Termed “precision oncoanalgesia,” this emerging field aims to elucidate how individual patient-specific tumor omics (genomics, transcriptomics, etc.) may mediate the effects of analgesic drugs on oncological recurrence and survival. © 2024 Elsevier Ltd |
| Keywords: | cancer survival; cancer surgery; review; cancer recurrence; multimodality cancer therapy; cancer patient; lung cancer; drug effect; transcriptomics; health care quality; narcotic analgesic agent; drug research; opioids; lung surgery; postoperative pain; personalized medicine; postoperative analgesia; futurology; non small cell lung cancer; process optimization; clinical outcome; oncologist; local anesthetics; adjuncts; human; precision medicine; oncogenomics; personalized cancer therapy; tumor genomics; perioperative medicine; drug utilization review |
| Journal Title: | Best Practice and Research: Clinical Anaesthesiology |
| Volume: | 38 |
| Issue: | 1 |
| ISSN: | 1521-6896 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2024-02-29 |
| Start Page: | 74 |
| End Page: | 80 |
| Language: | English |
| DOI: | 10.1016/j.bpa.2024.05.001 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | The MSK Cancer Center Support Grant (P30 CA008748) is acknowledge in the PDF -- Corresponding authors is MSK author: Alessia Pedoto -- Source: Scopus |
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