Susceptibility of healthcare personnel with severe acute respiratory coronavirus virus 2 (SARS-CoV-2) hybrid immunity to XBB lineage reinfection Journal Article


Authors: Whiting, K. A.; Guest, R.; Seshan, V. E.; Kamboj, M.
Article Title: Susceptibility of healthcare personnel with severe acute respiratory coronavirus virus 2 (SARS-CoV-2) hybrid immunity to XBB lineage reinfection
Abstract: Among 8,678 vaccinated healthcare personnel (HCP) with previous coronavirus disease 2019 (COVID-19), by August 28, 2023, 909 (10%) had an infection of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) omicron XBB variant. Reinfection risk was comparable irrespective of previous infection type except for the omicron BQ.1 variant. Bivalent vaccination had a protective effect. COVID-19 vaccines remain vital to protect HCP, including those with hybrid immunity. © The Author(s), 2024. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America.
Keywords: adult; middle aged; immunology; vaccination; health care personnel; immunity; tertiary health care; new york; disease predisposition; health personnel; vulnerable population; virus pathogenesis; workplace; reinfection; humans; human; male; female; article; heterologous immunity; severe acute respiratory syndrome coronavirus 2; coronavirus disease 2019; covid-19; sars-cov-2; covid-19 vaccines; positivity rate; sars-cov-2 vaccine; sars-cov-2 (lineage ba.2); sars-cov-2 (lineage ba.5); sars-cov-2 variants; full time employment; hybrid immunity; sars-cov-2 (lineage xbb); sars-cov-2 omicron (lineage bq.1); viral evolution
Journal Title: Infection Control and Hospital Epidemiology
Volume: 45
Issue: 6
ISSN: 0899-823X
Publisher: The Society for Healthcare Epidemiology of America  
Date Published: 2024-06-01
Start Page: 781
End Page: 784
Language: English
DOI: 10.1017/ice.2023.282
PUBMED: 38374682
PROVIDER: scopus
DOI/URL:
Notes: Article -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PDF -- MSK corresponding author is Karissa Whiting -- Source: Scopus
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MSK Authors
  1. Venkatraman Ennapadam Seshan
    382 Seshan
  2. Mini Kamboj
    158 Kamboj
  3. Rebecca Guest
    6 Guest
  4. Karissa A. Whiting
    47 Whiting