Remote symptom monitoring with clinical alerts following mastectomy: Do early symptoms predict 30-day surgical complications Journal Article


Authors: Chu, J. J.; Tadros, A. B.; Vingan, P. S.; Assel, M. J.; McCready, T. M.; Vickers, A. J.; Carlsson, S.; Morrow, M.; Mehrara, B. J.; Stern, C. S.; Pusic, A. L.; Nelson, J. A.
Article Title: Remote symptom monitoring with clinical alerts following mastectomy: Do early symptoms predict 30-day surgical complications
Abstract: Background: Electronic patient-reported outcome measures (ePROMs) for real-time remote symptom monitoring facilitate early recognition of postoperative complications. We sought to determine whether remote, electronic, patient-reported symptom-monitoring with Recovery Tracker predicts 30-day readmission or reoperation in outpatient mastectomy patients. Methods: We conducted a retrospective review of breast cancer patients who underwent outpatient (< 24-h stay) mastectomy with or without reconstruction from April 2017 to January 2022 and who received the Recovery Tracker on Days 1–10 postoperatively. Of 5,130 patients, 3,888 met the inclusion criteria (2,880 mastectomy with immediate reconstruction and 1,008 mastectomy only). We focused on symptoms concerning for surgical complications and assessed if symptoms reaching prespecified alert levels—prompting a nursing call—predicted risk of 30-day readmission or reoperation. Results: Daily Recovery Tracker response rates ranged from 45% to 70%. Overall, 1,461 of 3,888 patients (38%) triggered at least one alert. Most red (urgent) alerts were triggered by pain and fever; most yellow (less urgent) alerts were triggered by wound redness and pain severity. The 30-day readmission and reoperation rates were low at 3.8% and 2.4%, respectively. There was no statistically significant association between symptom alerts and 30-day reoperation or readmission, and a clinically relevant increase in risk can be excluded (odds ratio 1.08; 95% confidence interval 0.8–1.46; p = 0.6). Conclusions: Breast cancer patients undergoing mastectomy with or without reconstruction in the ambulatory setting have a low burden of concerning symptoms, even in the first few days after surgery. Patients can be reassured that symptoms that do present resolve quickly thereafter. © Society of Surgical Oncology 2024.
Keywords: retrospective studies; mastectomy; breast neoplasms; breast reconstruction; mammaplasty; retrospective study; postoperative complication; postoperative complications; breast tumor; reoperation; humans; human; female
Journal Title: Annals of Surgical Oncology
Volume: 31
Issue: 5
ISSN: 1068-9265
Publisher: Springer  
Date Published: 2024-05-01
Start Page: 3377
End Page: 3386
Language: English
DOI: 10.1245/s10434-024-15031-3
PUBMED: 38355780
PROVIDER: scopus
PMCID: PMC11790047
DOI/URL:
Notes: The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF -- Corresponding author is MSK author: Jonas A. Nelson -- Source: Scopus
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MSK Authors
  1. Monica Morrow
    772 Morrow
  2. Carrie Stern
    39 Stern
  3. Babak Mehrara
    448 Mehrara
  4. Andrew J Vickers
    880 Vickers
  5. Sigrid Viktoria Carlsson
    220 Carlsson
  6. Melissa Jean Assel
    110 Assel
  7. Jonas Allan Nelson
    208 Nelson
  8. Audree Blythe Tadros
    116 Tadros
  9. Jacqueline J. Chu
    27 Chu
  10. Perri S. Vingan
    20 Vingan