Imaging considerations before and after liver-directed locoregional treatments for metastatic colorectal cancer Review


Authors: Chlorogiannis, D. D.; Moussa, A. M.; Zhao, K.; Alexander, E. S.; Sofocleous, C. T.; Sotirchos, V. S.
Review Title: Imaging considerations before and after liver-directed locoregional treatments for metastatic colorectal cancer
Abstract: Colorectal cancer is a leading cause of cancer-related death. Liver metastases will develop in over one-third of patients with colorectal cancer and are a major cause of morbidity and mortality. Even though surgical resection has been considered the mainstay of treatment, only approximately 20% of the patients are surgical candidates. Liver-directed locoregional therapies such as thermal ablation, Yttrium-90 transarterial radioembolization, and stereotactic body radiation therapy are pivotal in managing colorectal liver metastatic disease. Comprehensive pre- and post-intervention imaging, encompassing both anatomic and metabolic assessments, is invaluable for precise treatment planning, staging, treatment response assessment, and the prompt identification of local or distant tumor progression. This review outlines the value of imaging for colorectal liver metastatic disease and offers insights into imaging follow-up after locoregional liver-directed therapy. © 2024 by the authors.
Keywords: colorectal cancer; imaging; margin; stereotactic body radiation therapy; liver metastases; thermal ablation; interventional oncology; locoregional therapy; yttrium-90 radioembolization
Journal Title: Diagnostics
Volume: 14
Issue: 7
ISSN: 2075-4418
Publisher: MDPI  
Date Published: 2024-04-01
Start Page: 772
Language: English
DOI: 10.3390/diagnostics14070772
PROVIDER: scopus
PMCID: PMC11011364
PUBMED: 38611685
DOI/URL:
Notes: The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF -- Corresponding author is MSK author: Vlasios S. Sotirchos -- Source: Scopus
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MSK Authors
  1. Amgad Mohamed Abdelhady Moussa
    34 Moussa
  2. Ken Zhao
    35 Zhao