Radioactive seed localization is a safe and effective tool for breast cancer surgery: an evaluation of over 25,000 cases Journal Article
| Authors: | Miodownik, D.; Bierman, D.; Thornton, C.; Moo, T.; Feigin, K.; Damato, A.; Le, T.; Williamson, M.; Prasad, K.; Chu, B.; Dauer, L.; Saphier, N.; Zanzonico, P.; Morrow, M.; Bellamy, M. |
| Article Title: | Radioactive seed localization is a safe and effective tool for breast cancer surgery: an evaluation of over 25,000 cases |
| Abstract: | Radioactive seed localization (RSL) provides a precise and efficient method for removing non-palpable breast lesions. It has proven to be a valuable addition to breast surgery, improving perioperative logistics and patient satisfaction. This retrospective review examines the lessons learned from a high-volume cancer center's RSL program after 10 years of practice and over 25 000 cases. We provide an updated model for assessing the patient's radiation dose from RSL seed implantation and demonstrate the safety of RSL to staff members. Additionally, we emphasize the importance of various aspects of presurgical evaluation, surgical techniques, post-surgical management, and regulatory compliance for a successful RSL program. Notably, the program has reduced radiation exposure for patients and medical staff. © 2024 Institute of Physics. All rights reserved. |
| Keywords: | retrospective studies; tumor localization; breast cancer; breast; radiotherapy; diagnostic imaging; breast neoplasms; retrospective study; radiation exposure; radioactive iodine; iodine radioisotopes; breast tumor; partial mastectomy; radioactivity; surgery; radiation safety; breast surgery; diseases; mastectomy, segmental; radiation dosimetry; effective tool; procedures; regulatory compliance; seed localization; humans; human; female; localisation; adioactive seed localization; mammography localization; tumour localization |
| Journal Title: | Journal of Radiological Protection |
| Volume: | 44 |
| Issue: | 1 |
| ISSN: | 0952-4746 |
| Publisher: | IOP Publishing Ltd |
| Date Published: | 2024-03-01 |
| Start Page: | 011511 |
| Language: | English |
| DOI: | 10.1088/1361-6498/ad246a |
| PUBMED: | 38295404 |
| PROVIDER: | scopus |
| PMCID: | PMC11701837 |
| DOI/URL: | |
| Notes: | Article -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PDF -- MSK corresponding author is M. Bellamy -- Source: Scopus |
