Authors: | Wisdom, A. J.; Barker, C. A.; Chang, J. Y.; Demaria, S.; Formenti, S.; Grassberger, C.; Gregucci, F.; Hoppe, B. S.; Kirsch, D. G.; Marciscano, A. E.; Mayadev, J.; Mouw, K. W.; Palta, M.; Wu, C. C.; Jabbour, S. K.; Schoenfeld, J. D. |
Review Title: | The next chapter in immunotherapy and radiation combination therapy: Cancer-specific perspectives |
Abstract: | Immunotherapeutic agents have revolutionized cancer treatment over the past decade. However, most patients fail to respond to immunotherapy alone. A growing body of preclinical studies highlights the potential for synergy between radiation therapy and immunotherapy, but the outcomes of clinical studies have been mixed. This review summarizes the current state of immunotherapy and radiation combination therapy across cancers, highlighting existing challenges and promising areas for future investigation. © 2024 Elsevier Inc. |
Keywords: | multimodality cancer therapy; combined modality therapy; neoplasm; neoplasms; radiotherapy; clinical study; immunotherapy; combination therapy; diseases; preclinical studies; humans; human; immunotherapeutics; 'current; growing bodies |
Journal Title: | International Journal of Radiation Oncology, Biology, Physics |
Volume: | 118 |
Issue: | 5 |
ISSN: | 0360-3016 |
Publisher: | Elsevier Inc. |
Date Published: | 2024-04-01 |
Start Page: | 1404 |
End Page: | 1421 |
Language: | English |
DOI: | 10.1016/j.ijrobp.2023.12.046 |
PUBMED: | 38184173 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Review -- Source: Scopus |