Resectable non-stage IV nonsmall cell lung cancer: The surgical perspective Review


Authors: Aigner, C.; Batirel, H.; Huber, R. M.; Jones, D. R.; Sihoe, A. D. L.; Štupnik, T.; Brunelli, A.
Review Title: Resectable non-stage IV nonsmall cell lung cancer: The surgical perspective
Abstract: Surgery remains an essential element of the multimodality radical treatment of patients with early-stage nonsmall cell lung cancer. In addition, thoracic surgery is one of the key specialties involved in the lung cancer tumour board. The importance of the surgeon in the setting of a multidisciplinary panel is ever-increasing in light of the crucial concept of resectability, which is at the base of patient selection for neoadjuvant/adjuvant treatments within trials and in real-world practice. This review covers some of the topics which are relevant in the daily practice of a thoracic oncological surgeon and should also be known by the nonsurgical members of the tumour board. It covers the following topics: the pre-operative selection of the surgical candidate in terms of fitness in light of the ever-improving nonsurgical treatment alternatives unfit patients may benefit from; the definition of resectability, which is so important to include patients into trials and to select the most appropriate radical treatment; the impact of surgical access and surgical extension with the evolving role of minimally invasive surgery, sublobar resections and parenchymal-sparing sleeve resections to avoid pneumonectomy. © The authors 2024.
Keywords: multimodality cancer therapy; combined modality therapy; cancer staging; neoplasm staging; carcinoma, non-small-cell lung; lung neoplasms; pneumonectomy; pathology; lung tumor; non small cell lung cancer; humans; human
Journal Title: European Respiratory Review
Volume: 33
Issue: 171
ISSN: 0905-9180
Publisher: European Respiratory Society  
Date Published: 2024-01-31
Start Page: 230195
Language: English
DOI: 10.1183/16000617.0195-2023
PUBMED: 38508666
PROVIDER: scopus
PMCID: PMC10951859
DOI/URL:
Notes: Review -- Source: Scopus
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  1. David Randolph Jones
    417 Jones