Predictive and prognostic biomarkers in breast tumours Review
| Authors: | Krystel-Whittemore, M.; Tan, P. H.; Wen, H. Y. |
| Review Title: | Predictive and prognostic biomarkers in breast tumours |
| Abstract: | In the age of precision medicine, extensive research has investigated tumour biomarkers to predict the behaviour of cancer and/or response to treatment in order to better understand the prognosis and treatment of disease. In breast cancer, significant progress has been made to categorise a common disease into subtypes defined by intrinsic tumour biology, measured by tumour biomarkers. This review encompasses the established biomarkers within breast cancer with the most up-to-date information regarding their understanding and clinical use as predictive and/or prognostic markers of breast cancer. © 2023 Royal College of Pathologists of Australasia |
| Keywords: | missense mutation; review; ki 67 antigen; breast cancer; estrogen responsive element; food and drug administration; pathology; breast neoplasms; tumor marker; gene rearrangement; microsatellite instability; breast tumor; hormonal therapy; neoadjuvant chemotherapy; estrogen receptor; progesterone receptor; ligand binding; differentiation; personalized medicine; molecular pathology; chromosome 14; cancer prognosis; breast pathology; invasive breast cancer; humans; prognosis; human; female; pembrolizumab; hormone receptor positive breast cancer; biomarkers, tumor; breast tissue; trastuzumab deruxtecan; neoplastic cell transformation; breast biomarkers; breast clinical oncology |
| Journal Title: | Pathology |
| Volume: | 56 |
| Issue: | 2 |
| ISSN: | 0031-3025 |
| Publisher: | Royal College of Pathologists of Australasia |
| Date Published: | 2024-03-01 |
| Start Page: | 186 |
| End Page: | 191 |
| Language: | English |
| DOI: | 10.1016/j.pathol.2023.10.014 |
| PUBMED: | 38212230 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF -- Source: Scopus |
