Exploring the utility of multiplex infectious disease panel testing for diagnosis of infection in different body sites: A joint report of the Association for Molecular Pathology, American Society for Microbiology, Infectious Diseases Society of America, and Pan American Society for Clinical Virology Review
| Authors: | Lewinski, M. A.; Alby, K.; Babady, N. E.; Butler-Wu, S. M.; Bard, J. D.; Greninger, A. L.; Hanson, K.; Naccache, S. N.; Newton, D.; Temple-Smolkin, R. L.; Nolte, F. |
| Review Title: | Exploring the utility of multiplex infectious disease panel testing for diagnosis of infection in different body sites: A joint report of the Association for Molecular Pathology, American Society for Microbiology, Infectious Diseases Society of America, and Pan American Society for Clinical Virology |
| Abstract: | The use of clinical molecular diagnostic methods for detecting microbial pathogens continues to expand and, in some cases, supplant conventional identification methods in various scenarios. Analytical and clinical benefits of multiplex molecular panels for the detection of respiratory pathogens have been demonstrated in various studies. The use of these panels in managing different patient populations has been incorporated into clinical guidance documents. The Association for Molecular Pathology's Infectious Diseases Multiplex Working Group conducted a review of the current benefits and challenges to using multiplex PCR for the detection of pathogens from gastrointestinal tract, central nervous system, lower respiratory tract, and joint specimens. The Working Group also discusses future directions and novel approaches to detection of pathogens in alternate specimen types, and outlines challenges associated with implementation of these multiplex PCR panels. © 2023 Association for Molecular Pathology and American Society for Investigative Pathology |
| Keywords: | united states; pathology, molecular; communicable disease; molecular pathology; molecular diagnosis; molecular diagnostic techniques; communicable diseases; procedures; multiplex polymerase chain reaction; humans; human |
| Journal Title: | Journal of Molecular Diagnostics |
| Volume: | 25 |
| Issue: | 12 |
| ISSN: | 1525-1578 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 2023-12-01 |
| Start Page: | 857 |
| End Page: | 875 |
| Language: | English |
| DOI: | 10.1016/j.jmoldx.2023.08.005 |
| PUBMED: | 37757952 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Source: Scopus |
