Regulatory T cells in the face of the intestinal microbiota Review


Authors: Ramanan, D.; Pratama, A.; Zhu, Y.; Venezia, O.; Sassone-Corsi, M.; Chowdhary, K.; Galván-Peña, S.; Sefik, E.; Brown, C.; Gélineau, A.; Mathis, D.; Benoist, C.
Review Title: Regulatory T cells in the face of the intestinal microbiota
Abstract: Regulatory T cells (Treg cells) are key players in ensuring a peaceful coexistence with microorganisms and food antigens at intestinal borders. Startling new information has appeared in recent years on their diversity, the importance of the transcription factor FOXP3, how T cell receptors influence their fate and the unexpected and varied cellular partners that influence Treg cell homeostatic setpoints. We also revisit some tenets, maintained by the echo chambers of Reviews, that rest on uncertain foundations or are a subject of debate. © 2023, Springer Nature Limited.
Journal Title: Nature Reviews Immunology
Volume: 23
Issue: 11
ISSN: 1474-1733
Publisher: Nature Publishing Group  
Date Published: 2023-11-01
Start Page: 749
End Page: 762
Language: English
DOI: 10.1038/s41577-023-00890-w
PUBMED: 37316560
PROVIDER: scopus
DOI/URL:
Notes: Review -- Source: Scopus
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  1. Chrysothemis Celia Margaret Brown
    17 Brown