Epidermal reconstruction during ex vivo confocal microscopy for detection of superficial basal cell carcinoma with 3D-mosaicking and intensity projection Book Section
| Authors: | Moronta, M.; Harris, U.; Sendín-Martín, M.; Bang, A.; Rossi, A.; Lee, E.; Nehal, K.; Chen, C. S. J.; Rajadhyaksha, M.; Kose, K.; Jain, M. |
| Editors: | Jain, M.; Rossi, A.; Nehal, K.; Sendín-Martín, M. |
| Article/Chapter Title: | Epidermal reconstruction during ex vivo confocal microscopy for detection of superficial basal cell carcinoma with 3D-mosaicking and intensity projection |
| Abstract: | Ex vivo confocal microscopy (EVCM) allows rapid evaluation of freshly excised tissue margins with high sensitivity and specificity for residual basal cell carcinoma (BCC) during Mohs surgery. A major limitation encountered in these studies has been the inability to flatten peripheral edges of excised tissue, affecting the evaluation of superficial BCCs. A few mechanical devices have been used to physically flatten the tissue specimens, but these have not been sufficient. Herein, we describe a non-mechanical digital approach of 3D-mosaicking and intensity projection for complete visualization of the epidermal margin. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022. |
| Keywords: | mohs surgery; matlab; 3d-mosaicking; epidermal margin; ex vivo confocal microscopy; flattening; epidermal reconstruction |
| Book Title: | Cutaneous Atlas of Ex Vivo Confocal Microscopy |
| ISBN: | 978-3-030-89315-6 |
| Publisher: | Springer Nature |
| Publication Place: | Cham, Switzerland |
| Date Published: | 2022-01-01 |
| Start Page: | 169 |
| End Page: | 175 |
| Language: | English |
| DOI: | 10.1007/978-3-030-89316-3_17 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Book Chapter: 17 -- Section of "Part VII: Future of Ex Vivo Confocal Microscopy" -- Source: Scopus |
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