Short-term follow-up of contrast-enhanced mammography lesions after negative breast MRI in women with elevated breast cancer risk Journal Article
| Authors: | Coffey, K.; Dixon, L. B.; Sevilimedu, V.; Jochelson, M. S.; Sung, J. S. |
| Article Title: | Short-term follow-up of contrast-enhanced mammography lesions after negative breast MRI in women with elevated breast cancer risk |
| Abstract: | Purpose: To determine the outcome of enhancing lesions detected on contrast-enhanced mammography (CEM) that had no correlate on magnetic resonance imaging (MRI) and underwent short-term follow-up CEM. Methods: In this retrospective single-center study, we identified patients with elevated breast cancer risk who had a CEM between 2014 and 2021 showing indeterminate enhancement on recombined images (BI-RADS 0, 3, 4) that had no correlate on subsequent MRI (performed within one month), and therefore underwent short-term follow-up CEM (performed within eight months). Medical records and imaging studies were reviewed to collect data on patient and lesion characteristics, and outcomes. Cancer incidence with 95% confidence interval (CI) was calculated. Results: This study included 71 women (median age 49 years) with 81 enhancing CEM lesions who underwent short-term follow-up CEM (median 6.2 months) after MRI reported no correlate. Of 81 lesions (median size = 0.7 cm), 73 (90%) were non-mass enhancement and 8 (10%) were enhancing masses. No sonographic correlate was identified for 75 lesions that had a same-day targeted ultrasound. Two cancers (2.5%, 95% CI 0.3–8.6) were diagnosed during the short-term follow-up period, one at 6-months (invasive ductal carcinoma) and one at 12-months (ductal carcinoma in situ). The remaining 79 lesions were benign at 6-month follow-up CEM and at one-year mammographic follow-up. Conclusions: Follow-up CEM of MRI-occult lesions is prudent and may be reasonable to perform at one-year given the low incidence of cancer detected at six-months (one of 81) in our small study sample. © 2023 Elsevier B.V. |
| Keywords: | magnetic resonance imaging; breast neoplasms; mammography |
| Journal Title: | European Journal of Radiology |
| Volume: | 168 |
| ISSN: | 0720-048X |
| Publisher: | Elsevier B.V |
| Date Published: | 2023-11-01 |
| Start Page: | 111097 |
| Language: | English |
| DOI: | 10.1016/j.ejrad.2023.111097 |
| PROVIDER: | scopus |
| PUBMED: | 37738835 |
| DOI/URL: | |
| Notes: | Corresponding MSK author is Kristen Coffey -- Source: Scopus |
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