Authors: | Cabric, V.; Brown, C. C. |
Title: | Thymic mimicry: The art of imitation |
Abstract: | Display of tissue self-antigens within the thymus is critical for the regulation of self-reactive T cells. In this issue of JEM, Michelson et al. (2023. J. Exp. Med.https://doi.org/10.1084/jem.20230461) continue to advance our understanding of self-antigen representation by medullary thymic epithelial cells, identifying a new role for Hnf4γ in the regulation of thymic mimetic cells as well as their peripheral counterparts. © 2023 Cabric and Brown. |
Keywords: | thymus; thymus gland; epithelium cell; epithelial cells; autoantigen; autoantigens; imitative behavior; imitation |
Journal Title: | Journal of Experimental Medicine |
Volume: | 220 |
Issue: | 10 |
ISSN: | 0022-1007 |
Publisher: | Rockefeller University Press |
Date Published: | 2023-10-02 |
Start Page: | e20231010 |
Language: | English |
DOI: | 10.1084/jem.20231010 |
PUBMED: | 37516920 |
PROVIDER: | scopus |
PMCID: | PMC10374940 |
DOI/URL: | |
Notes: | Article -- Source: Scopus |