Axillary lymph node dissection: Dead or still alive? Review

   


Authors: Beck, A. C.; Morrow, M.
Review Title: Axillary lymph node dissection: Dead or still alive?
Abstract: Although sentinel lymph node biopsy is now the primary method of axillary staging and is therapeutic for patients with limited nodal disease, axillary lymph node dissection (ALND) is still necessary for staging in groups where sentinel lymph node biopsy has not been proven to be accurate and to maintain local control in those with a heavy axillary tumor burden. Additionally, newer approaches to systemic therapy tailored to risk level sometimes necessitate knowledge of the number of involved axillary nodes which can only be obtained with ALND. Ongoing trials will address whether there are additional circumstances where radiotherapy can replace ALND. © 2023
Keywords: treatment response; survival rate; overall survival; systemic therapy; cancer radiotherapy; disease free survival; cancer staging; lymph node dissection; lymph nodes; neoplasm staging; lymph node excision; sentinel lymph node biopsy; treatment indication; metastasis; breast cancer; mastectomy; tumor volume; pathology; breast neoplasms; cancer hormone therapy; tumor burden; breast tumor; lymph node; micrometastasis; neoadjuvant chemotherapy; axilla; postmenopause; axillary lymph node dissection; triple negative breast cancer; breast-conserving surgery; macrometastasis; lymph vessel metastasis; human epidermal growth factor receptor 2 positive breast cancer; humans; human; female; article; pembrolizumab; hormone receptor positive breast cancer; abemaciclib; axillary surgery; de-escalation; breast radiotherapy; human epidermal growth factor receptor 2 negative breast cancer; limit 6): axillary lymph node dissection
Journal Title: Breast
Volume: 69
ISSN: 0960-9776
Publisher: Elsevier Inc.  
Date Published: 2023-06-01
Start Page: 469
End Page: 475
Language: English
DOI: 10.1016/j.breast.2023.01.009
PUBMED: 36702672
PROVIDER: scopus
PMCID: PMC10300611
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85146651853&doi=10.1016%2fj.breast.2023.01.009&partnerID=40&md5=94f3aa5466dc5009e3e5fb42e0fcc43a
Notes: Article -- Source: Scopus
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MSK Authors
  1. Monica Morrow
    773 Morrow
  2. Anna C Beck
    5 Beck
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