Perspectives in immunotherapy: Meeting report from Immunotherapy Bridge (Naples, November 30th–December 1st, 2022) Editorial


Authors: Ascierto, P. A.; Avallone, A.; Bifulco, C.; Bracarda, S.; Brody, J. D.; Emens, L. A.; Ferris, R. L.; Formenti, S. C.; Hamid, O.; Johnson, D. B.; Kirchhoff, T.; Klebanoff, C. A.; Lesinski, G. B.; Monette, A.; Neyns, B.; Odunsi, K.; Paulos, C. M.; Powell, D. J. Jr; Rezvani, K.; Segal, B. H.; Singh, N.; Sullivan, R. J.; Fox, B. A.; Puzanov, I.
Title: Perspectives in immunotherapy: Meeting report from Immunotherapy Bridge (Naples, November 30th–December 1st, 2022)
Abstract: The discovery and development of novel treatments that harness the patient’s immune system and prevent immune escape has dramatically improved outcomes for patients across cancer types. However, not all patients respond to immunotherapy, acquired resistance remains a challenge, and responses are poor in certain tumors which are considered to be immunologically cold. This has led to the need for new immunotherapy-based approaches, including adoptive cell transfer (ACT), therapeutic vaccines, and novel immune checkpoint inhibitors. These new approaches are focused on patients with an inadequate response to current treatments, with emerging evidence of improved responses in various cancers with new immunotherapy agents, often in combinations with existing agents. The use of cell therapies, drivers of immune response, and trends in immunotherapy were the focus of the Immunotherapy Bridge (November 30th–December 1st, 2022), organized by the Fondazione Melanoma Onlus, Naples, Italy, in collaboration with the Society for Immunotherapy of Cancer. © 2023, The Author(s).
Keywords: biomarkers; immunotherapy; combination therapy; vaccine; tumor microenvironment; checkpoint inhibitors
Journal Title: Journal of Translational Medicine
Volume: 21
ISSN: 1479-5876
Publisher: Biomed Central Ltd  
Date Published: 2023-07-20
Start Page: 488
Language: English
DOI: 10.1186/s12967-023-04329-7
PROVIDER: scopus
PMCID: PMC10360352
PUBMED: 37475035
DOI/URL:
Notes: Article -- Source: Scopus
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