MIRD pamphlet No. 28, Part 1: MIRDcalc-A software tool for medical internal radiation dosimetry Journal Article

   


Authors: Kesner, A. L.; Carter, L. M.; Ocampo Ramos, J. C.; Lafontaine, D.; Olguin, E. A.; Brown, J. L.; President, B.; Jokisch, D. W.; Fisher, D. R.; Bolch, W. E.
Article Title: MIRD pamphlet No. 28, Part 1: MIRDcalc-A software tool for medical internal radiation dosimetry
Abstract: Medical internal radiation dosimetry constitutes a fundamental aspect of diagnosis, treatment, optimization, and safety in nuclear medicine. The MIRD committee of the Society of Nuclear Medicine and Medical Imaging developed a new computational tool to support organ-level and suborgan tissue dosimetry (MIRDcalc, version 1). Based on a standard Excel spreadsheet platform, MIRDcalc provides enhanced capabilities to facilitate radiopharmaceutical internal dosimetry. This new computational tool implements the well-established MIRD schema for internal dosimetry. The spreadsheet incorporates a significantly enhanced database comprising details for 333 radionuclides, 12 phantom reference models (International Commission on Radiological Protection), 81 source regions, and 48 target regions, along with the ability to interpolate between models for patient-specific dosimetry. The software also includes sphere models of various composition for tumor dosimetry. MIRDcalc offers several noteworthy features for organ-level dosimetry, including modeling of blood source regions and dynamic source regions defined by user input, integration of tumor tissues, error propagation, quality control checks, batch processing, and report-preparation capabilities. MIRDcalc implements an immediate, easy-to-use single-screen interface. The MIRDcalc software is available for free download (www.mirdsoft.org) and has been approved by the Society of Nuclear Medicine and Molecular Imaging. © 2023 by the Society of Nuclear Medicine and Molecular Imaging.
Keywords: radiotherapy dosage; publication; dosimetry; radiometry; radioisotope; software; radioisotopes; radiobiology; pamphlets; procedures; radionuclide therapy; research methods; mird; humans; human
Journal Title: Journal of Nuclear Medicine
Volume: 64
Issue: 7
ISSN: 0161-5505
Publisher: Society of Nuclear Medicine  
Date Published: 2023-07-01
Start Page: 1117
End Page: 1124
Language: English
DOI: 10.2967/jnumed.122.264225
PUBMED: 37268428
PROVIDER: scopus
PMCID: PMC10315701
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85164209323&doi=10.2967%2fjnumed.122.264225&partnerID=40&md5=68ecb5187de9380a55bc3900243d4114
Notes: Article -- Addendum added, see DOI: 10.2967/jnumed.123.266325 -- Source: Scopus
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MSK Authors
  1. Adam Leon Kesner
    68 Kesner
  2. Lukas M Carter
    79 Carter
  3. Daniel Lafontaine
    21 Lafontaine
  4. Juan Camilo Ocampo Ramos
    27 Ocampo Ramos
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