Factors determining esthetic outcome after breast cancer conservative treatment Journal Article


Authors: Cardoso, M. J.; Cardoso, J.; Santos, A. C.; Vrieling, C.; Christie, D.; Liljegren, G.; Azevedo, I.; Johansen, J.; Rosa, J.; Amaral, N.; Saaristo, R.; Sacchini, V.; Barros, H.; Oliveira, M. C.
Article Title: Factors determining esthetic outcome after breast cancer conservative treatment
Abstract: The aim of this study was to evaluate the factors that determine esthetic outcome after breast cancer conservative treatment, based on a consensual classification obtained with an international consensus panel. Photographs were taken from 120 women submitted to conservative unilateral breast cancer surgery (with or without axillary surgery) and radiotherapy. The images were sent to a panel of observers from 13 different countries and consensus on the classification of esthetic result (recorded as excellent, good, fair or poor) was obtained in 113 cases by means of a Delphi method. For each patient, data were collected retrospectively regarding patient characteristics, tumor, and treatment factors. Univariate and multivariate analysis were used to evaluate the correlation between these factors and overall cosmetic results. On univariate analysis, younger and thinner patients as well as patients with lower body mass index (BMI) and premenopausal status obtained better cosmetic results. In the group of tumor- and treatment-related factors, larger removed specimens, clearly visible scars, the use of chemotherapy and longer follow-up period were associated with less satisfactory results. On multivariate analysis, only BMI and scar visibility maintained a significant association with cosmesis. BMI and scar visibility are the only factors significantly associated with cosmetic results of breast cancer conservative treatment, as evaluated by an international consensus panel.
Keywords: treatment outcome; evaluation; adjuvant chemotherapy; delphi method; local-control; stage-i; mammary-cancer; no boost trial; eortc boost; breast cancer conservation; esthetic result; subjective; primary radiation-therapy; conserving treatment; cosmetic assessment; consensus methods
Journal Title: Breast Journal
Volume: 13
Issue: 2
ISSN: 1075-122X
Publisher: Wiley Blackwell  
Date Published: 2007-03-01
Start Page: 140
End Page: 146
Language: English
ACCESSION: WOS:000244341600005
DOI: 10.1111/j.1524-4741.2007.00394.x
PROVIDER: wos
PUBMED: 17319854
Notes: --- - Article - "Source: Wos"
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  1. Virgilio Sacchini
    146 Sacchini