Authors: | Pennings, I.; Moskowitz, A.; Shah, G.; Estilo, C.; Huryn, J. M.; Yom, S. K. |
Article Title: | Osteonecrosis of the jaw associated with pembrolizumab |
Abstract: | We report a case of osteonecrosis of the jaw (ONJ) with pembrolizumab, a rare yet possibly emerging complication. In this case, a temporal relationship between the development of ONJ and the patient's treatment regimen suggested an association between pembrolizumab/GVD therapy and the development of ONJ. Thrombocytosis and anatomic factors may also have played a role. The number of patients using pembrolizumab will likely continue to increase. We document this instance in order to better inform dental treatment around cancer patients undergoing pembrolizumab therapy. © 2023 Elsevier Inc. |
Journal Title: | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology |
Volume: | 136 |
Issue: | 1 |
ISSN: | 2212-4403 |
Publisher: | Elsevier B.V. |
Date Published: | 2023-07-01 |
Start Page: | e11 |
End Page: | e14 |
Language: | English |
DOI: | 10.1016/j.oooo.2022.12.013 |
PROVIDER: | scopus |
PUBMED: | 36804060 |
PMCID: | PMC10395506 |
DOI/URL: | |
Notes: | Article -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PubMed and PDF -- MSK corresponding author is SaeHee Yom -- Source: Scopus |