Fertility-sparing options for cancer patients Review


Authors: Alur-Gupta, S.; Fruchtman, H.; Paroder, V.
Review Title: Fertility-sparing options for cancer patients
Abstract: Fertility preservation is becoming an integral part of cancer care among women of reproductive age. Despite advances in the treatment of pelvic malignancies, all the currently available treatment approaches, including radiotherapy, chemotherapy, and surgery, place women at high risk for future fertility impairment. With improved long-term survival rates associated with cancer, expanding the reproductive options available is of high priority. Several fertility preservation options are available today for women with gynecologic and non-gynecologic malignancies. Depending on the underlying oncological entity, these can include the following procedures whether alone or in combination: oocyte cryopreservation, embryo cryopreservation, ovarian tissue cryopreservation, ovarian transposition, and trachelectomy. The purpose of this review is to provide the most up-to-date information on the aforementioned fertility-preserving approaches and highlight the current challenges, drawbacks, and areas of research where more data are still very necessary to optimize outcomes in young female oncological patients desiring pregnancy in the future. © 2023, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
Keywords: cancer surgery; review; cancer patient; endometrium cancer; neoplasm; neoplasms; oocyte; oocytes; ovary cancer; ovary; cryopreservation; pregnancy; premenopause; gynecologic surgery; trachelectomy; female fertility; myomectomy; oocyte retrieval; fertility preservation; female genital tract cancer; procedures; ovary hyperstimulation; ovarian transposition; humans; human; female; cervicotomy; ovarian hyperstimulation; gestational carrier
Journal Title: Abdominal Radiology
Volume: 48
Issue: 5
ISSN: 2366-004X
Publisher: Springer  
Date Published: 2023-05-01
Start Page: 1618
End Page: 1628
Language: English
DOI: 10.1007/s00261-023-03839-8
PUBMED: 36884058
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 31 May 2023 -- Source: Scopus
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  1. Viktoriya Paroder
    60 Paroder