Abstract: |
Uterine transposition has emerged as an alternative technique for fertility preservation in young women with pelvic malignancies who need pelvic radiation. It was developed from adapting well-established surgical techniques (ovarian transposition and radical trachelectomy) with the goal of keeping the uterus and adnexa outside the radiotherapy field in order to preserve their function. Briefly, before radiotherapy, the uterine ligaments and uterine artery are sectioned and the uterus is detached from the vagina and transposed together with tubes and ovaries to the superior abdomen as a flap, using the gonadal vessels for blood supply. The uterus along with intact tubes and ovaries are placed back to its natural position after completion of radiation therapy. The cervix is re-anastomosed to the vagina and the ligaments reconstructed. Preliminary data suggest that uterine transposition is a feasible option for selected patients with pelvic cancer that require pelvic radiotherapy. Oncologic and fertility outcomes are pending. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2022. |