De-intensification strategies for head and neck cancer Book Section

  


Authors: Strohl, M. P.; Ha, P. K.; Zakeri, K.; Lee, N.
Editors: Chandra, R. A.; Li, R. J.
Article/Chapter Title: De-intensification strategies for head and neck cancer
Abstract: Human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) is an epidemiologically, pathologically, and clinically distinct form of cancer of the head and neck. It is associated with a significantly better prognosis and overall survival than its HPV-negative counterpart. Patients presenting with this disease are usually younger, healthier, and without the usual risk factors of aerodigestive tract malignancy such as significant smoking or alcohol use. As such, there has been a focus on reducing treatment toxicities and optimizing quality of life while maintaining favorable oncologic outcomes. This chapter provides the rationale behind de-intensification strategies, an overview of approaches to de-intensification and limitations to de-intensification. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.
Keywords: radiotherapy; head and neck cancer; oropharynx; human papillomavirus; transoral surgery; hpv-related oropharyngeal cancer; de-intensification
Book Title: Multidisciplinary Management of Head and Neck Cancer: Contemporary Applications and Techniques
ISBN: 978-3-031-05972-8
Publisher: Springer  
Publication Place: Cham, Switzerland
Date Published: 2022-01-01
Start Page: 1
End Page: 12
Language: English
DOI: 10.1007/978-3-031-05973-5_1
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85158979605&doi=10.1007%2f978-3-031-05973-5_1&partnerID=40&md5=3a4c29278a1865ec02640f9b54a4b654
Notes: Book Chapter: 1 -- Source: Scopus
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MSK Authors
  1. Nancy Y. Lee
    878 Lee
  2. Kaveh Zakeri
    83 Zakeri
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