Watch-and-wait approach to rectal cancer: The role of imaging Review
| Authors: | Jayaprakasam, V. S.; Alvarez, J.; Omer, D. M.; Gollub, M. J.; Smith, J. J.; Petkovska, I. |
| Review Title: | Watch-and-wait approach to rectal cancer: The role of imaging |
| Abstract: | The diagnosis and treatment of rectal cancer have evolved dramatically over the past several decades. At the same time, its incidence has increased in younger populations. This review will inform the reader of advances in both diagnosis and treatment. These advances have led to the watch-and-wait approach, otherwise known as nonsurgical management. This review briefly outlines changes in medical and surgical treatment, advances in MRI technology and interpretation, and landmark studies or trials that have led to this exciting juncture. Herein, the authors delve into current state-of-the-art methods to assess response to treatment with MRI and endoscopy. Currently, these methods for avoiding surgery can be used to detect a complete clinical response in as many as 50% of patients with rectal cancer. Finally, the limitations of imaging and endoscopy and future challenges will be discussed. © RSNA, 2023. |
| Keywords: | treatment outcome; neoadjuvant therapy; nuclear magnetic resonance imaging; magnetic resonance imaging; neoplasm recurrence, local; diagnostic imaging; watchful waiting; tumor recurrence; rectal neoplasms; rectum tumor; chemoradiotherapy; procedures; adjuvant chemoradiotherapy; chemoradiotherapy, adjuvant; humans; human |
| Journal Title: | Radiology |
| Volume: | 307 |
| Issue: | 1 |
| ISSN: | 0033-8419 |
| Publisher: | Radiological Society of North America, Inc. |
| Date Published: | 2023-04-01 |
| Start Page: | e221529 |
| Language: | English |
| DOI: | 10.1148/radiol.221529 |
| PUBMED: | 36880951 |
| PROVIDER: | scopus |
| PMCID: | PMC10068893 |
| DOI/URL: | |
| Notes: | Review -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PDF -- MSK corresponding author is Marc Gollub -- Export Date: 1 May 2023 -- Source: Scopus |
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