Evaluation of women with a positive urine cytology and no demonstrable disease in the urinary tract Review


Authors: Donat, S. M.; Sonoda, Y.; Al-Ahmadie, H.; Murali, R.; Ng, D. L.; Funt, S. A.; Park, K. J.
Review Title: Evaluation of women with a positive urine cytology and no demonstrable disease in the urinary tract
Abstract: Urinary cytology is indispensable both for the evaluation of gross hematuria and surveillance of patients with urothelial neoplasms. A positive urine cytology usually indicates the presence of urothelial carcinoma somewhere in the urinary tract. However, in women, it may also signal urothelial carcinoma involvement of the lower gynecologic tract or be the presenting sign for a primary cancer of the lower gynecologic tract or rectum. Guidelines for the evaluation of women with a positive cytology and normal urinary tract are lacking. We present a review of the current literature with case scenarios to bring clinicians attention to this diagnostic dilemma. © 2023 Elsevier Inc.
Keywords: cytology; pathology; bladder tumor; urinary bladder neoplasms; urologic neoplasms; urine; carcinoma, transitional cell; transitional cell carcinoma; urinary tract; urinary tract tumor; humans; human; female
Journal Title: Urology
Volume: 173
ISSN: 0090-4295
Publisher: Elsevier Science, Inc.  
Date Published: 2023-03-01
Start Page: 10
End Page: 16
Language: English
DOI: 10.1016/j.urology.2022.12.032
PUBMED: 36621649
PROVIDER: scopus
DOI/URL:
Notes: The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF. Corresponding author is MSK author Sherri M. Donat -- Source: Scopus
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MSK Authors
  1. Sherri M Donat
    174 Donat
  2. Yukio Sonoda
    472 Sonoda
  3. Kay Jung Park
    305 Park
  4. Rajmohan Murali
    219 Murali
  5. Samuel Aaron Funt
    136 Funt
  6. Dianna L. Ng
    20 Ng