Elevated soluble urokinase plasminogen activator receptor is associated with renal dysfunction in a Chlorocebus atheiops COVID-19 model Journal Article
| Authors: | Gonzalez, A. A.; Olsen, E. L.; Killeen, S. Z.; Blair, R. V.; Seshan, S. V.; Jaimes, E. A.; Roy, C. J.; Prieto, M. C. |
| Article Title: | Elevated soluble urokinase plasminogen activator receptor is associated with renal dysfunction in a Chlorocebus atheiops COVID-19 model |
| Abstract: | Increases of soluble urokinase plasminogen activator receptor (suPAR) were measured in both urine and plasma of a Chlorocebus aethiops (African green monkey; AGM) mucosal infected with SARS-CoV-2. The data indicate that elevated suPAR may be associated with renal dysfunction and pathology in the context of COVID-19. © 2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. |
| Keywords: | case report; biomarkers; biological marker; animal; animals; kidney disease; urokinase receptor; complication; acute kidney injury; kidney diseases; renal injury; chlorocebus aethiops; nonhuman primate; covid-19; sars-cov-2; receptors, urokinase plasminogen activator; african green monkey |
| Journal Title: | Journal of Medical Primatology |
| Volume: | 52 |
| Issue: | 2 |
| ISSN: | 0047-2565 |
| Publisher: | Wiley Blackwell |
| Date Published: | 2023-04-01 |
| Start Page: | 131 |
| End Page: | 134 |
| Language: | English |
| DOI: | 10.1111/jmp.12626 |
| PUBMED: | 36377612 |
| PROVIDER: | scopus |
| PMCID: | PMC10023264 |
| DOI/URL: | |
| Notes: | Article -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PubMed and PDF -- Source: Scopus |
