Addressing the challenges of penicillin allergy delabeling with electronic health records and mobile applications Review


Authors: Powell, N.; Elkhalifa, S.; Guyer, A.; Garcez, T.; Sandoe, J.; Zhou, L.
Review Title: Addressing the challenges of penicillin allergy delabeling with electronic health records and mobile applications
Abstract: Allergy labels are common, often incorrect, and potentially harmful. There are many opportunities for clinical decision support (CDS) tools integrated in the electronic health record (EHR) and mobile apps to address the challenges with drug allergy management, including penicillin allergy delabeling (PADL). Effective delabeling solutions must consider multidisciplinary clinical workflow and multistep processes, including documentation, assessment, plan (eg, allergy testing and referral), record update, drug allergy alert management, and allergy reconciliation over time. Developing a systematic infrastructure to manage allergies across the EHR is critical to improve the accuracy and completeness of a patient's allergy and avoid inadvertently relabeling. Improving the appropriateness and relevancy of drug allergy alerts is important to reduce alert fatigue. Using alerts to guide clinicians on appropriate antibiotic use may reduce unnecessary β-lactam avoidance. To date, EHR CDS tools have facilitated non-allergists to provide PADL at the point of care. A mobile app was shown to support PADL and provide specialist support and education. Future research is needed to standardize, integrate, and evaluate innovative CDS tools in the EHR to demonstrate patient safety and clinical utility and facilitate wider adoption. © 2022 American Academy of Allergy, Asthma & Immunology
Keywords: drug hypersensitivity; antiinfective agent; anti-bacterial agents; patient safety; penicillin derivative; hypersensitivity; electronic health records; penicillins; antimicrobial stewardship; humans; human; electronic health record; clinical decision support; mobile applications; penicillin allergy; mobile application; mobile telephone applications; penicillin allergy delabeling
Journal Title: Journal of Allergy and Clinical Immunology: In Practice
Volume: 11
Issue: 2
ISSN: 2213-2198
Publisher: Elsevier B.V.  
Date Published: 2023-02-01
Start Page: 414
End Page: 421
Language: English
DOI: 10.1016/j.jaip.2022.10.037
PUBMED: 36356924
PROVIDER: scopus
DOI/URL:
Notes: Article -- Source: Scopus
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  1. Autumn Chandler Guyer
    6 Guyer