Cord blood grafts for patients with HIV? Editorial
| Author: | Scaradavou, A. |
| Title: | Cord blood grafts for patients with HIV? |
| Abstract: | Since CCR5 is a key co-receptor for HIV entry into cells, replacing an HIV patient's cells with CCR5-deficient cells is thought to protect the new hematopoietic/immune system from infection. In this issue of Cell, Hsu et al. show that transplanting a cord blood graft carrying the CCR5Δ32 mutation led to a durable HIV remission in a patient with HIV and leukemia. © 2023 Elsevier Inc. |
| Keywords: | genetics; mutation; clinical feature; note; human immunodeficiency virus infection; risk factor; cord blood stem cell transplantation; fetal blood; fetus blood; immune response; remission; hiv infections; human immunodeficiency virus 1; hiv-1; chemokine receptor ccr5; mortality rate; receptors, ccr5; humans; human |
| Journal Title: | Cell |
| Volume: | 186 |
| Issue: | 6 |
| ISSN: | 0092-8674 |
| Publisher: | Cell Press |
| Date Published: | 2023-03-16 |
| Start Page: | 1101 |
| End Page: | 1102 |
| Language: | English |
| DOI: | 10.1016/j.cell.2023.01.024 |
| PUBMED: | 36931240 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Note -- Source: Scopus |
